149017-69-6

Usage

InChI:InChI=1/C23H28O5/c1-22(2)26-19-20(25-15-18-12-8-5-9-13-18)23(3,28-21(19)27-22)16-24-14-17-10-6-4-7-11-17/h4-13,19-21H,14-16H2,1-3H3/t19-,20+,21+,23-/m1/s1

Upstream product

• 2595-05-3 Diacetone D-glucose 
• 582-52-5 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 2847-00-9 1,2:5,6-di-O-isopropylidene-α-D-hexofuran-3-ulose 
• 956485-06-6 3-O-(2-naphthylmethyl)-1,2:5,6-di-O-isopropylidene-α-D-allofuranose 
• 100-39-0 benzyl bromide 
• 956485-08-8 ((3aR,5R,6S,6aR)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyl-6-(naphthalen-2-ylmethoxy)tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanol 
• 956485-07-7 ((3aR,6S,6aR)-2,2-dimethyl-6-(naphthalen-2-ylmethoxy)tetrahydrofuro[3,2-d][1,3]dioxole-5,5-diyl)dimethanol 
• 1057385-93-9 (3aR,5S,6R,6aR)-2,2-dimethyl-6-(naphthalen-2-ylmethoxy)tetrahydrofuro[3,2-d][1,3]dioxole-5-carbaldehyde 
• 1091607-89-4 (R)-1-((3aR,5R,6R,6aR)-2,2-dimethyl-6-(naphthalen-2-ylmethoxy)tetrahydrofuro[3,2-d][1,3]dioxol-5-yl)ethane-1,2-diol 
• 153186-10-8 ((3aR,5R,6S,6aR)-6-(benzyloxy)-5-((benzyloxy)methyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanol 
• 63593-03-3 1,2-O-isopropylidene-3-O-benzyl-4-hydroxymethyl-α-D-ribofuranose 
• 100-44-7 benzyl chloride 
• 153186-14-2 3,5-di-O-benzyl-4-C-iodomethyl-1,2-O-isopropylidene-α-D-ribofuranose 

Downstream Products

• 153186-29-9 4'-C-methylcytidine 
• 153186-26-6 1-(4-C-methyl-β-D-ribofuranosyl)-uracil 
• 160766-52-9 3',5'-di-O-benzyl-4'-C-methyladenosine 
• 153186-24-4 2'-O-acetyl-3',5'-di-O-benzyl-4'-C-methyluridine 
• 153186-25-5 2'-O-acetyl-3',5'-di-O-benzyl-4'-C-methyl-β-D-ribofuranosylthymine 
• 153186-30-2 N⁶-benzoyl-2'-O-acetyl-3',5'-di-O-benzyl-4'-C-methyladenosine 
• 794517-46-7 1-O-methyl-3,5-di-O-benzyl-4-C-methylribofuranose 
• 153186-16-4 1,2,5-di-O-acetyl-3-O-benzyl-4-C-methyl-α-D-ribofuranose 
• 153186-15-3 1,2-di-O-acetyl-3,5-di-O-benzyl-4-C-methyl-α-D-ribofuranose 

Relevant academic research and scientific papers

PYRROLO[1,2-f][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS

Provided herein are formulations, methods and substituted tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds of Formula (I) for treating Pneumovirinae virus infections, including respiratory syncytial virus infections, as well as methods and intermediates for synthesis of tetrahydrofuranyl-pyrrolo[1,2-f][1,2,4]triazine-4-amine compounds.

Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase

The present invention provides nucleoside compounds and certain derivatives thereof which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-d

Synthesis of 4'-C-methylnucleosides.

Several 4'-C-methylnucleosides were prepared. 1H-NMR studies on these nucleotides showed that they have the 3'-exo furanose ring conformation different from the 3'-endo conformation of natural nucleosides.