153325-42-9

Basic information

• Product Name: 4,6-di-O-benzoyl-myo-inositol
• Synonyms: 4,6-di-O-benzoyl-myo-inositol
• CAS NO: 153325-42-9
• Molecular Weight: 388.374
• Mol File: 153325-42-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4,6-di-O-benzoyl-myo-inositol(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-di-O-benzoyl-myo-inositol(153325-42-9)
• EPA Substance Registry System: 4,6-di-O-benzoyl-myo-inositol(153325-42-9)

Safety Data

• Hazardous Substances Data: 153325-42-9(Hazardous Substances Data)

Upstream product

• 113584-86-4 (+/-)-1,4-di-O-benzyl-myo-inositol 
• 98-88-4 benzoyl chloride 
• 98510-20-4 myo-Inositol orthoformate 

Downstream Products

• 153265-90-8 (-)-1D-1-O-butyryl-4,6-O-dibenzoyl-myo-inositol 
• 153265-91-9 C₂₇H₃₀O₉ 
• 134932-19-7 (+)-1D-1,2,4,5,6-O-pentabenzoyl-myo-inositol 
• 176589-79-0 C₄₀H₄₀O₁₀ 
• 176589-78-9 1D-2-O-acetyl-1-O-butyryl-4,6-O-dibenzoyl-myo-inositol 
• 176589-80-3 Benzoic acid (1R,2S,3S,4R,5S,6R)-2,6-bis-benzyloxy-3,4,5-trihydroxy-cyclohexyl ester 

Relevant articles and documents

Syntheses of myo-inositol-1,2,3,5- and 2,4,5,6-tetrakisphosphates, unusual inhibitors of myo-inositol-1,4,5-trisphosphae 3-kinase

D-myo-Inositol 1,4,5-trisphosphate [D-I(1,4,5)P3], a calcium mobilizing second messenger, is converted to D-I(1,3,4,5)P4 by D-I(1,4,5)P3-3-kinase. Efficient syntheses of I(1,2,3,5)P4 (2) and I(2,4,5,6)P4 (3), novel 3-kinase inhibitors, are reported.

Synthesis of All Possible Regioisomers of myo-Inositol Tetrakisphosphates

Synthesis of all possible nine regioisomers of IP4, some of which are implicated as second messengers in the cellular signalling, was accomplished from myo-inositol via its dibenzoate derivatives (IBz2) as the key intermediates; base-catalysed isomerization of readily available I(1,4)Bz2 and its derivatives, followed by suitable separation procedures efficiently provided all nine regioisomers of IBz2.