153391-40-3Relevant articles and documents
Photophysical and electrochemical studies of highly fluorescent pyrazole and imidazole containing heterocycles
Maurya, Hardesh K.,Kumar, Ch. Pavan,Chandrasekharam,Gupta, Atul
, p. 686 - 696 (2016/09/28)
Highly congested pyrazole and imidazole ring containing heterocycles were studied for their photophysical and electrochemical properties. TDDFT calculations of the molecules were carried out using B3LYP/G(d,p) level theory in DMF medium and the results we
Studies on substituted benzo[h]quinazolines, benzo[g]indazoles, pyrazoles, 2,6-diarylpyridines as anti-tubercular agents
Maurya, Hardesh K.,Verma, Ruby,Alam, Saba,Pandey, Shweta,Pathak, Vinay,Sharma, Sandeep,Srivastava, Kishore K.,Negi, Arvind S.,Gupta, Atul
, p. 5844 - 5849 (2013/10/22)
Various substituted 5,6-dihydro-8-methoxybenzo[h]quinazolin-2-amine, 1-(3-(4-alkoxyphenyl)-7-methoxy-3,3a,4,5-tetrahydro-2H benzo[g]indazol-2-yl) ethanone, pyrazole and 2,6-diarylpyridine derivatives have been synthesized in good yields by an efficient me
Synthesis of E- and Z-Pyrazolylacrylonitriles and their evaluation as novel antioxidants
Parmar, Virinder S.,Kumar, Ajay,Prasad, Ashok K.,Singh, Sanjay K.,Kumar, Naresh,Mukherjee, Shubhasish,Raj, Hanumantharao G.,Goel, Sanjay,Errington, William,Puar, Mohindar S.
, p. 1425 - 1436 (2007/10/03)
A facile synthesis of (Z)- and (E)-2-(5-arylpyrazol-3-yl)-3-(pyrrol-2-yl)acrylonitriles and (Z)-2-(1,3-diarylpyrazol-5-yl)-3-(pyrrol-2-yl)acrylonitriles, and isomerisation of (Z)-2-(5-arylpyrazolyl)acrylonitriles to (E)-2-(5-arylpyrazolyl)acrylonitriles under basic conditions have been reported. (Z)-2-(1,3-Diarylpyrazolyl)acrylonitriles did not undergo isomerisation under the similar conditions. New compounds were identified on the basis of their spectral data (1H-, 13C-, 1H-1H COSY, NOESY, NOE, HMQC NMR, IR, UV and EI mass). The structures of one acrylonitrile and five of their precursor 6-arylpyran-2-ones and cyanomethylpyrazoles were confirmed by X-ray crystallographic studies. Effects of pyrazolylacrylonitriles and their precursors on rat liver-microsomal lipid peroxidation were evaluated in vitro with a view to establish structure-activity relationship and to identify a lead compound. Copyright (C) 1999 Elsevier Science Ltd.