153463-29-7Relevant academic research and scientific papers
Asymmetric synthesis of α-keto β-lactams via [2+2] cycloaddition reaction: A concise approach to optically active α-hydroxy β-lactams and β-alkyl(aryl)isoserines
Palomo,Aizpurua,Miranda,Mielgo,Odriozola
, p. 6325 - 6328 (1993)
The cycloaddition reaction of the Evans-Sjogren ketenes to imines, followed by α-hydroxylation of the resulting cycloadducts provides an efficient general asymmetric synthesis of α-keto β-lactams and derivatives.
