153475-15-1Relevant academic research and scientific papers
Design and synthesis of promiscuous high-affinity monoamine transporter ligands: Unraveling transporter selectivity
Greiner, Elisabeth,Boos, Terrence L.,Prisinzano, Thomas E.,De Martino, Maria G.,Zeglis, Brian,Dersch, Christina M.,Marcus, Jamila,Partilla, John S.,Rothman, Richard B.,Jacobson, Arthur E.,Rice, Kenner C.
, p. 1766 - 1772 (2006)
A series of 4-[2-[bis(4-fluorophenyl)methoxy]ethyl]-piperidines and 4-[2-[(bisphenyl)methoxy]ethyl]-piperidines with different types of substituents in the phenylpropyl side-chain were synthesized and examined for their ability to bind to the dopamine tra
Development of a robust immobilized organocatalyst for the redox-neutral mitsunobu reaction
Lai, Junshan,Llanes, Patricia,Mastandrea, Marco M.,Pericàs, Miquel A.,Perulli, Stefania,Zhou, Leijie
supporting information, p. 8859 - 8864 (2021/11/23)
A polystyrene-supported version of the Denton catalyst for redox-neutral Mitsunobu reactions, (2-hydroxybenzyl)diphenylphosphine oxide, has been developed and used in catalytic inversion of enantiopure secondary alcohols (21 examples, up to 97% yield and 98% ee) with 2-nitrobenzoic and 2,4-dinitrobenzoic acids. The use in the reaction of alternative pronucleophiles has also been explored (8 successful and 3 unsuccessful examples). The functional resin shows high recyclability (10 cycles, 30 days operation) and can be re-activated by simple treatment with butylamine with further extension of its useful life.
A CATALYTIC ENANTIOSELECTIVE SYNTHESIS OF CHIRAL MONOSUBSTITUTED OXIRANES
Corey, E. J.,Helal, Christopher J.
, p. 5227 - 5230 (2007/10/02)
A new catalytic enentioselective synthesis of monosubstituted oxiranes has been developed from achiral trichloromethyl ketones by (a) enentioselective carbonyl reduction, (b) selective bis-dechlorination and (c) base-induced ring closure of the resulting chlorohydrins.
