153492-11-6

Basic information

• Product Name: N-(5-Amino-pentyl)-N-benzyloxy-succinamic acid methyl ester
• CAS NO: 153492-11-6
• Molecular Weight: 322.404
• Mol File: 153492-11-6.mol

Chemical Properties

• CAS DataBase Reference: N-(5-Amino-pentyl)-N-benzyloxy-succinamic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-Amino-pentyl)-N-benzyloxy-succinamic acid methyl ester(153492-11-6)
• EPA Substance Registry System: N-(5-Amino-pentyl)-N-benzyloxy-succinamic acid methyl ester(153492-11-6)

Safety Data

• Hazardous Substances Data: 153492-11-6(Hazardous Substances Data)

Upstream product

• 153492-08-1 1-<(tert-Butoxycarbonyl)amino>-5-<(trichloroethoxycarbonyl)(benzyloxy)amino>pentane 
• 153492-09-2 1-<(tert-Butoxycarbonyl)amino>-5-<(benzyloxy)amino>pentane 
• 153492-10-5 N-Benzyloxy-N-(5-tert-butoxycarbonylamino-pentyl)-succinamic acid methyl ester 
• 83948-54-3 tert-butyl (5-bromopentyl)carbamate 
• 75178-90-4 N-(tert-butyloxycarbonyl)-5-aminopentanol 
• 90195-00-9 N-<(2,2,2-trichloroethoxy)carbonyl>-O-benzylhydroxylamine 

Downstream Products

• 153492-20-7 2-{[5-(Acetyl-benzyloxy-amino)-pentylcarbamoyl]-methyl}-N-{5-[benzyloxy-(3-methoxycarbonyl-propionyl)-amino]-pentyl}-2-hydroxy-succinamic acid tert-butyl ester 

Relevant articles and documents

Synthesis of Novel Citrate-Based Siderophores and Siderophore-β-Lactam Conjugates. Iron Transport-Mediated Drug Delivery Systems

The synthesis of analogs of arthrobactin (5), a microbial iron chelator, and its imide 8 are described.The differentially protected citric acid residue 31 served as the key intermediate in making conjugates having a generalized structure 14 with two representative carbacephalosporin units, 15 and 16.Both conjugates, 49 and 51, showed antibiotic activity, while conjugate 51 obtained from β-lactam 16 bearing a phenylglycyl side chain was shown to be more effective.