110128-36-4

Upstream product

• 110128-33-1 2-benzoyl-7-benzyloxy-6-methoxy-1-methylene-1,2,3,4-tetrahydroisoquinoline 
• 15357-92-3 6-methoxy-7-(benzyloxy)-3,4-dihydroisoquinoline 
• 71885-44-4 4,5-dihydro-4,4-dimethyl-2-(2-methylphenyl)-2-oxazoline 
• 22231-61-4 2-[4-(benzyloxy)-3-methoxyphenyl]ethylamine 
• 7154-66-7 2-bromobenzoic acid chloride 
• 39731-97-0 N-2-(4-benzyloxy-3-methoxyphenyl)ethylacetamide 
• 98-88-4 benzoyl chloride 
• 78867-50-2 7-(benzyloxy)-6-methoxy-1-methyl-3,4-dihydroisoquinoline 
• 133056-47-0 (7-Benzyloxy-6-methoxy-1-methylene-3,4-dihydro-1H-isoquinolin-2-yl)-(2-bromo-phenyl)-methanone 

Downstream Products

• 98988-24-0 (S)-2-Benzyloxy-3-methoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline 

Relevant academic research and scientific papers

2-(o-tolyl)-4,4-dimethyl-2-oxazolines - A new vehicle for facile convergent synthesis of protoberberine alkaloids

A single step synthesis of 8-oxotetrahydroprotoberberines (57-82%) by the addition of lithiated 2-(o-tolyl)-4,4-dimethyl-2-oxazolines on 3,4- dihydroisoquinolines is described.

A RADICAL APPROACH TO BHARATAMINE, A UNIQUE PROTOBERBERINE ALKALOID FROM ALANGIUM LAMARCKII

Bharatamine, a unique racemic protoberberine alkaloid from Alangium Lamarckii, has been synthesized via aryl radical-initiated 1,6-cyclization as the key step.

Bharatamine A Novel Protoberberine Alkaloid of Aberrant Biogenetic Origin from Alangium lamarckii Thw.

The structure elucidation and the synthesis of bharatamine, a biogenetic marvel being a protoberberine alkaloid unoxygenated in ring D, and its regioisomer isobharatamine have been discussed in detail.