1860-56-6

Basic information

• Product Name: 4-BENZYLOXY-3-METHOXY-OMEGA-NITROSTYRENE
• Synonyms: 2-(benzyloxy)-5-(2-nitrovinyl)-anisol;2-(benzyloxy)-5-(2-nitrovinyl)anisole;2-methoxy-4-(2-nitroethenyl)-1-(phenylmethoxy)-benzen;4-(benzyloxy)-3-methoxy-beta-nitro-styren;4-benzyloxy-3-methoxy-beta-nitrostyrene;4-BENZYLOXY-3-METHOXY-NITROSTYRENE;4-BENZYLOXY-3-METHOXY-OMEGA-NITROSTYRENE;1-(4-BENZYLOXY-3-METHOXYPHENYL)-2-NITROETHENE
• CAS NO: 1860-56-6
• Molecular Formula: C₁₆H₁₅NO₄
• Molecular Weight: 285.29
• Product Categories: Aromatics
• Mol File: 1860-56-6.mol
• Article Data: 29

Chemical Properties

• Melting Point: 122-124 °C(lit.)
• Boiling Point: 450.5°C at 760 mmHg
• Flash Point: 191.8°C
• Appearance: /
• Density: 1.212g/cm³
• Vapor Pressure: 6.99E-08mmHg at 25°C
• Refractive Index: 1.607
• Solubility: Acetic Acid, Dichloromethane, Ethyl Acetate, Methanol
• CAS DataBase Reference: 4-BENZYLOXY-3-METHOXY-OMEGA-NITROSTYRENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BENZYLOXY-3-METHOXY-OMEGA-NITROSTYRENE(1860-56-6)
• EPA Substance Registry System: 4-BENZYLOXY-3-METHOXY-OMEGA-NITROSTYRENE(1860-56-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: BZ8440000
• Hazardous Substances Data: 1860-56-6(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Solid

InChI:InChI=1/C16H15NO4/c1-20-16-11-13(9-10-17(18)19)7-8-15(16)21-12-14-5-3-2-4-6-14/h2-11H,12H2,1H3/b10-9-

Upstream product

• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 121-33-5 vanillin 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 75-52-5 nitromethane 
• 60372-07-8 1-(3-methoxy-4-benzyloxyphenyl)-2-nitroethanol 

Downstream Products

• 21473-46-1 2-(4'-benzyloxy-3'-methoxyphenyl)-1-nitroethane 
• 1306747-18-1 (R)-7-(benzyloxy)-4-(4-(benzyloxy)phenyl)-1,2,3,4-tetrahydro-6-methoxy-2-methyl isoquinoline 
• 1306747-17-0 1-(benzyloxy)-4(R )-(1-(4-(benzyloxy)-3-methoxyphenyl)-2-nitroethyl)benzene 
• 1263211-41-1 (S)-1-(4-methoxymethoxybenzyl)-2-methyl-6-methoxy-7-benzyloxy-1,2,3,4-tetrahydroisoquinoline 
• 1263210-09-8 7-(benzyloxy)-2-[(4R)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]-6-methoxy-1,2,3,4-tetrahydroisoquinoline 
• 1263210-03-2 2-[4,5-dihydro-4-((R)-1-methylethyl)-2-oxazolyl]-(S)-1-(4-methoxymethoxybenzyl)-6-methoxy-7-benzyloxy-1,2,3,4-tetrahydroisoquinoline 
• 1263210-04-3 (S)-1-(4-methoxymethoxybenzyl)-2-formyl-6-methoxy-7-benzyloxy-1,2,3,4-tetrahydroisoquinoline 
• 1263210-10-1 (S)-l-(4-methoxymethoxybenzyl)-6-methoxy-7-benzyloxy-1,2,3,4-tetrahydro-isoquinoline 
• 15357-92-3 6-methoxy-7-(benzyloxy)-3,4-dihydroisoquinoline 
• 55803-41-3 N-formyl-2-[3-methoxy-4-(benzyloxy)phenyl]ethylamine 
• 17958-52-0 (S)-1-(4-hydroxybenzyl)-2-methyl-6-methoxy-7-benzyloxy-1,2,3,4-tetrahydro-isoquinoline 
• 736124-05-3 1-(2',5'-dimethoxy)benzyl-6-methoxy-7-benzyloxy-3,4-dihydro-isoquinoline 
• 1373281-69-6 1-(2',5'-dimethoxy)benzyl-6-methoxy-7-benzyloxy-1,2,3,4-tetrahydro-isoquinoline 
• 1415466-32-8 S-(-)-2-benzyloxy-3,9,12-trimethoxy-5,8,13,13a-tetrahydro-6H-dibenzo[a,g]quinolizine 

Relevant articles and documents

Cactus alkaloids. XXXIII. β-Phenethylamines from the Guatemalan cactus Pilosocereus maxonii

TLC analysis of extracts of Pilosocereus maxonii (Rose) Byles and Rowley detected six identifiable alkaloids. Preparative TLC aided in the crystallization of the hydrochlorides of N-methyl-3,4-dimethoxyphenethylamine, N-methyl-3-methoxytyramine, and N,N-dimethyl-3-methoxytyramine. Traces of 3,4-dimethoxyphenethylamine (TLC and mass spectrometry), tyramine (TLC), and N-methyltyramine (TLC) were identified. While all of these compounds were isolated and/or detected previously in other cactus species this study is the first reported crystallization of N-methyl- and N,N-dimethyl-3-methoxytyramine from a natural source.

Design, synthesis and evaluation of benzo[a]thieno[3,2-g]quinolizines as novel l-SPD derivatives possessing dopamine D1, D2 and serotonin 5-HT1A multiple action profiles

A novel scaffold derived from l-SPD with a substituted thiophene group in the D ring were designed, synthesized, and evaluated for their binding affinities at dopamine (D1, D2 and D3) and serotonin (5-HT1A and 5

Full-synthetic method of racemic tetrandrine

The invention discloses a full-synthetic method of racemic tetrandrine, and belongs to the technical field of drug synthesis. The full-synthetic method of the racemic tetrandrine comprises the steps that a synthetic route adopts a convergence synthesis method, a 5-bromovanillin, namely a compound 1 and 3-hydroxy-4-methoxyphenylacetic acid, namely a compound 5 are taken as starting materials to obtain a compound 4 and a compound 6 respectively, then the compound 4 and the compound 6 are taken as raw materials to synthesize a compound 11, a compound 19 is synthesized from the compound 11, and finally, the compound 11 reacts with the compound 19. The full-synthetic method of the racemic tetrandrine has the advantages that the synthetic efficiency is higher, the yield is higher, and the cost is lower; the reaction conditions are milder, the operation is simple and convenient, the industrial value is higher, and a reference is provided for the full-synthetic method of optical voidness tetrandrine.

ZrCl4-mediated synthesis of 1,2,3-triazoles from vinyl nitrates and their biological evaluation

A ZrCl4-mediated simple method for the conversion of vinyl nitrates to 1,2,3-triazoles in excellent yields is developed. The obtained new triazoles were evaluated for their antimicrobial activity.