153829-27-7Relevant academic research and scientific papers
HETEROARYL SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS
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, (2019/03/15)
Compounds having the following formula (I) or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a monocyclic heteroaryl group, and R1, R3, R4, R5 and R6 are as defined herein, are useful as kinase modulators, including IRAK-4 inhibition.
Total Synthesis of Mugineic Acid. Efficient Use of the Phenyl Group as the Carboxyl Synthon
Matsuura, Fumiyoshi,Hamada, Yasumasa,Shioiri, Takayuki
, p. 8211 - 8222 (2007/10/02)
Stereoselective total synthesis of mugineic acid (1), a unique phytosiderophore from roots of barley, has been achieved from readily available (2S,3S)- and (2R,3R)-2,3-epoxycinnamyl alcohols (5) and (6).The key step is the oxidation of the phenyl group to the carboxylic acid by use of the ruthenium trichloride-sodium metaperiodate system.
A short enantioselective synthesis of N-Boc-α-amino acids from epoxy alcohols
Poch, Marta
, p. 7781 - 7784 (2007/10/02)
A new and efficient enantioselective synthesis of Boc-α-amino acids has been developed. Starting from an enantiomerically enriched epoxy alcohol the sequence involves a regioselective nucleophilic epoxide opening by diphenylmethylamine (benzhydrilamine), hydrogenolysis/ protection of the amino group, and oxidation of the diol moiety.
Efficient Synthesis of Mugineic Acid, A Typical Phytosiderophore, Utilizing the Phenyl Group as the Carboxyl Synthon
Matsuura, Fumiyoshi,Hamada, Yasumasa,Shioiri, Takayuki
, p. 7917 - 7920 (2007/10/02)
Stereoselective total synthesis of mugineic acid, a unique phytosiderophore from roots of barley, has been achieved from (2R,3R)- and (2S,3S)-2,3-epoxycinnamyl alcohols employing the phenyl group as the carboxyl synthon.
