15394-83-9 Usage
Description
2-(2,4,5-trimethoxyphenyl)ethanamine is a chemical compound belonging to the phenethylamine family, characterized by its molecular formula C11H17NO3. 2-(2,4,5-trimethoxyphenyl)ethanamine features a benzene ring with three methoxy groups attached, which contributes to its unique chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Research:
2-(2,4,5-trimethoxyphenyl)ethanamine is used as a research probe for the serotonin 5-HT2A receptor due to its ability to stimulate the receptor. This property makes it a valuable tool for studying the receptor's role in various physiological and pathological processes.
Used in Drug Development:
2-(2,4,5-trimethoxyphenyl)ethanamine has potential applications in the development of new drugs for the treatment of neurological and psychiatric disorders. Its interaction with the serotonin 5-HT2A receptor suggests that it may be useful in the treatment of conditions such as schizophrenia, depression, and anxiety disorders.
Used in Chemical Synthesis:
As a derivative of phenethylamine, 2-(2,4,5-trimethoxyphenyl)ethanamine can be used as a starting material or intermediate in the synthesis of other related compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Analytical Chemistry:
The unique chemical properties of 2-(2,4,5-trimethoxyphenyl)ethanamine, such as its reactivity and spectroscopic characteristics, may be exploited in analytical chemistry for the development of new methods for the detection, quantification, or separation of related compounds or other substances of interest.
Check Digit Verification of cas no
The CAS Registry Mumber 15394-83-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,3,9 and 4 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 15394-83:
(7*1)+(6*5)+(5*3)+(4*9)+(3*4)+(2*8)+(1*3)=119
119 % 10 = 9
So 15394-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H17NO3/c1-13-9-7-11(15-3)10(14-2)6-8(9)4-5-12/h6-7H,4-5,12H2,1-3H3
15394-83-9Relevant articles and documents
Synthesis and physicochemical and neurotoxicity studies of 1-(4-substituted-2,5-dihydroxyphenyl)-2-aminoethane analogues of 6-hydroxydopamine
Cheng,Castagnoli Jr.
, p. 513 - 520 (2007/10/02)
In an attempt to evaluate the possible relationship between the neurotoxicity of 6-hydroxydopamine and the redox properties and electrophilic reactivity of the 6-hydroxydopamine-p-hydroquinone/p-quinone system, we have synthesized a series of 6-hydroxydopamine analogues in which the C4-hydroxy group is replaced with various electron-donating and electron-withdrawing substituents. With the aid of cyclic voltammetry, the formal oxidation potentials (E°') for the p-hydroquinone/p-quinone redox couples and the rates of cyclization of the p-quinones to the corresponding p-iminoquinones were determined. As expected, electron-rich p-hydroquinones were easily oxidized to the p-quinones, which underwent cyclization slowly, whereas the oxidation of electron-poor p-hydroquinones required higher voltages and yielded p-quinones, which cyclized readily at pH 7.4. The neurotoxic potential of these compounds showed that in vivo destruction of noradrenergic terminals, as measured by inhibition of norepinephrine uptake by rat heart slices, occurred only with those analogues bearing electron-donating substituents. Potent neurotoxic properties were associated only with the 4-amino and 4-hydroxy derivatives, both of which form p-quinones, which do not cyclize readily at pH 7.4. These results support the thesis that the p-quinone derived from 6-hydroxydopamine may be an important species in the mediation of the neurodestruction caused by 6-hydrodopamine.
