15410-83-0

Basic information

• Product Name: 2-(naphthalen-2-yl)butanoic acid
• CAS NO: 15410-83-0
• Molecular Formula: C₁₄H₁₄O₂
• Molecular Weight: 214.2598
• Mol File: 15410-83-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 378.8°C at 760 mmHg
• Flash Point: 275.6°C
• Density: 1.159g/cm³
• Vapor Pressure: 2.06E-06mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 2-(naphthalen-2-yl)butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(naphthalen-2-yl)butanoic acid(15410-83-0)
• EPA Substance Registry System: 2-(naphthalen-2-yl)butanoic acid(15410-83-0)

Safety Data

• Hazardous Substances Data: 15410-83-0(Hazardous Substances Data)

Usage

General Description

2-(naphthalen-2-yl)butanoic acid is a chemical compound with a molecular formula C14H14O2. It is a derivative of butyric acid and contains a naphthalene group. 2-(naphthalen-2-yl)butanoic acid is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceutical intermediates. It has also been studied for its potential anti-inflammatory and analgesic properties. Additionally, 2-(naphthalen-2-yl)butanoic acid has been investigated for its potential role in the treatment of neurological disorders and as a potential bioactive compound. Overall, this compound has a range of potential applications and is of interest in various fields of research.

Upstream product

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Relevant articles and documents

Photoinduced Copper-Catalyzed Asymmetric Decarboxylative Alkynylation with Terminal Alkynes

We describe a photoinduced copper-catalyzed asymmetric radical decarboxylative alkynylation of bench-stable N-hydroxyphthalimide(NHP)-type esters of racemic alkyl carboxylic acids with terminal alkynes, which provides a flexible platform for the construction of chiral C(sp3)?C(sp) bonds. Critical to the success of this process are not only the use of the copper catalyst as a dual photo- and cross-coupling catalyst but also tuning of the NHP-type esters to inhibit the facile homodimerization of the alkyl radical and terminal alkyne, respectively. Owing to the use of stable and easily available NHP-type esters, the reaction features a broader substrate scope compared with reactions using the alkyl halide counterparts, covering (hetero)benzyl-, allyl-, and aminocarbonyl-substituted carboxylic acid derivatives, and (hetero)aryl and alkyl as well as silyl alkynes, thus providing a vital complementary approach to the previously reported method.

Carbonylative Transformation of Allylarenes with CO Surrogates: Tunable Synthesis of 4-Arylbutanoic Acids, 2-Arylbutanoic Acids, and 4-Arylbutanals

In this Communication, procedures for the selective synthesis of 4-arylbutanoic acids, 2-arylbutanoic acids, and 4-arylbutanals from the same allylbenzenes have been developed. With formic acid or TFBen as the CO surrogate, reactions proceed selectively and effectively under carbon monoxide gas-free conditions.