154160-16-4

Upstream product

• 95437-43-7 (S)-2-(N,N-dibenzylamino)-3-phenylpropanoic acid 
• 37610-80-3 1,3-dioxolan-2-ylethylmagnesium bromide 
• 131150-35-1 (S)-2-(dibenzylamino)-N'-methoxy-N'-methyl-3-phenylpropane amide 

Downstream Products

• 153353-99-2 (4S,5S)-5-tert-Butoxycarbonylamino-4-hydroxy-6-phenyl-hexanoic acid 
• 154160-25-5 (2R,4S,5S)-5-tert-Butoxycarbonylamino-4-hydroxy-2-methyl-6-phenyl-hexanoic acid 
• 133333-27-4 tert-butyl (1S)-1-[(2S)-5-oxotetrahydrofuran-2-yl]-2-phenylethylcarbamate 
• 143337-98-8 (5S,1'S)-5-(1'-(dibenzylamino)-2'-phenylethyl)dihydrofuran-2(3H)-one 
• 98818-45-2 5(S)-(Boc-amino)-4(S)-hydroxy-6-phenyl-2(R)-phenylmethylhexanoic acid 
• 154160-19-7 (2S,3S)-2-Dibenzylamino-5-[1,3]dioxolan-2-yl-1-phenyl-pentan-3-ol 

Relevant academic research and scientific papers

Stereoselective Synthesis of a Hydroxyethylene Dipeptide Isostere

A stereoselective synthesis of a hydroxyethylene dipeptide isostere for Phe-Gly, (4S, 5S)-4-hydroxy-5-amino-6-phenylhexanoic acid, is described.The use of dibenzyl protecting groups on ketoamine 5 accounts for the selectivity on reduction.Also, the dibenzyl group plays a role in directing the introduction of a third chiral center.