154228-35-0

Upstream product

• 164122-53-6 Methyl 2--3-methylbutanoate 
• 106-95-6 allyl bromide 
• 6306-52-1 L-valine methylester hydrochloride 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 949021-03-8 N-[1(S)-(4-methoxyphenyl)-3-buten-1-yl]-(S)-valinol 
• 188425-29-8 (1S)-1-(4-methoxyphenyl)but-3-en-1-amine 
• 949021-22-1 (S)-N-[1-(4-methoxyphenyl)-3-buten-1-yl]propenamide 

Relevant academic research and scientific papers

Enantioselective Synthesis of Homoallylic Amines. Evidence of Reversible Addition of Allylzinc Bromide to Aromatic Imines Derived from (S)-Valine Methyl Ester and (S)-Valinol

The reaction of aromatic and aliphatic imines derived from (S)-valine methyl ester and (S)-valinol with allyl bromide and zinc in tetrahydrofuran affords homoallylic amines with up to 100percent diastereoisomeric excess (d.e.), but in the case of the arom

Asymmetric synthesis of δ-substituted α,β-unsaturated δ-lactams by ring closing metathesis of enantiomerically pure N-acryloyl-homoallylic amines

(Chemical Equation Presented) Optically pure secondary homoallylic amines, obtained by highly diastereoselective addition of allylmetal reagents to imines derived from chiral amines, were N-dealkylated, and the primary amines were converted to N-acryloyl

Enantioselective Synthesis of Homoallylic Amines by Addition of Allylmetal Reagents to Imines Derived from (S)-Valine Esters

Grignard and Barbier procedures have been applied to the addition of allylmethal (Zn, Cu, Pb, Bi, Al, In) species to imines derived from (S)-valine esters, principally the methyl ester.The Zn-mediated, CeCl3- or SnCl2-catalyzed "Barbier" reactions of the