1546-80-1Relevant articles and documents
Preparation method of 4-chloro-2-trifluoromethyl pyrimidine
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Paragraph 0021, (2017/07/20)
The invention discloses a preparation method of 4-chloro-2-trifluoromethyl pyrimidine (formula I). According to the preparation method, cheap and easily purchased methyl trifluoroacetate and malonamide are taken as the raw materials. The preparation method has the advantages that no pricy material is used, the reaction conditions are mild, the used equipment is simple, the EHS risk is little, the cost is low, and the preparation method is suitable for massive production.