154709-19-0

Basic information

• Product Name: 4-(2-Cyanophenyl)benzyl alcohol
• Synonyms: 4-(2-Cyanophenyl)benzyl alcohol;Irbesartan IMpurity C;2-[4-(hydroxymethyl)phenyl]benzonitrile
• CAS NO: 154709-19-0
• Molecular Formula: C₁₄H₁₁NO
• Molecular Weight: 209.24
• Mol File: 154709-19-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 4-(2-Cyanophenyl)benzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Cyanophenyl)benzyl alcohol(154709-19-0)
• EPA Substance Registry System: 4-(2-Cyanophenyl)benzyl alcohol(154709-19-0)

Safety Data

• Hazardous Substances Data: 154709-19-0(Hazardous Substances Data)

Usage

Uses

2-[4-(Hydroxymethyl)phenyl]benzonitrile is an impurity of 4’-Bromomethyl-2-cyanobiphenyl (B685335), which is used in protein-binding studies of quinoxaline angiotensin II receptor antagonists.

Upstream product

• 50-00-0 formaldehyd 
• 24973-49-7 biphenyl-2-carbonitrile 
• 72037-57-1 (E)-2-benzylidene-1,1-dimethylhydrazine 
• 1404116-63-7 (E)-2'-[(2,2-dimethylhydrazono)methyl]-[1,1'-biphenyl]-4-carbaldehyde 
• 1122-91-4 4-bromo-benzaldehyde 
• 114772-54-2 4'-(bromomethyl)-1,1'-biphenyl-2-carbonitrile 
• 873-75-6 4-bromobenzenemethanol 
• 214360-47-1 2-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-benzonitrile 

Downstream Products

• 151052-40-3 2'-(1H-tetrazol-5-yl)biphenyl-4-carbaldehyde 
• 160514-13-6 5-(4'-hydroxymethyl-biphenyl-2-yl)-1H-tetrazole 
• 135689-93-9 4-(2-Cyanophenyl)benzaldehyde 
• 154709-18-9 4'-hydroxymethyl-2-(N-trityl-1H-tetrazol-5-yl)biphenyl 
• 124750-51-2 N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole 
• 160514-13-6 2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-methanol 

Relevant articles and documents

Preparation of 5 - (4 the [...] -bromo methyl-2-biphenyl) - 1-trityl tetrazazole method

The invention discloses a method for preparing 5-(4'-bromomethyl-2-biphenyl)-1-triphenyl methyl tetrazole. According to the method, 2-cyano biphenyl is used for replacing 2-cyano 4'-methyl biphenyl in the conventional process and is used as a starting material, and a target product, the 5-(4'-bromomethyl-2-biphenyl)-1-triphenyl methyl tetrazole, is obtained by means of hydroxymethylation, cyclization, protection, and substitution reaction. The method has the advantages of low cost of the raw materials, convenience for recovery of solvent, less comprehensive pollution and the like and is suitable for industrialized production.

PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES

The present invention relates to a method for preparing substituted tetrazoles, compounds obtained according to this method, new reactants and new tetrazole derivatives.

Imidazole derivatives having a II antagonist activity

Imidazole derivatives having A II antagonist activity, of Formula I, the processes for the preparation thereof, pharmaceutical compositions containing them and the use thereof as therapeutic agents. The described compounds having A II antagonist activity