154802-24-1Relevant academic research and scientific papers
Stereoselectivite comparee de la reduction de trifluoromethylcetones et des methylcetones correspondantes: nouvelles voies d'acces a des derives trifluoromethyles de pentoses
Munier, Pascal,Krusinski, Aniela,Picq, Dominique,Anker, Daniel
, p. 1229 - 1244 (2007/10/02)
The selectivity of the reduction of some trifluoroacetyl-1,3-dioxanes and 1,3-dioxolanes with DIBAH or L-Selectride was studied and compared with that the corresponding methylketones; the results -in accordance with literature- show an important steric hi
Trifluoromethylation of Sugar 1,4-Lactones: Synthesis of 5-Deoxy-5,5,5-Trifluoro-D and L-Ribose and Lyxose Derivatives
Munier, Pascal,Picq, Dominique,Anker, Daniel
, p. 8241 - 8244 (2007/10/02)
The four 5-deoxy-5,5,5-trifluoro-D and L-ribo and -lyxo furanoses were synthesized from lactones using CF3SiMe3 in 5 or 6 steps and 30-40percent overall yield.The key step was a stereoselective reduction of 1,1,1-trifluoro-2-ketoses with LiAlH4 or NaBH4 a
