154865-79-9

Upstream product

• 74-87-3 methylene chloride 
• 138381-85-8 1,5-dideoxy-1,5-[{(phenylmethoxy)carbonyl}imino]-4 6-O-(R-phenylmethylene)-D-glucitol, 2-benzoate 
• 130539-12-7 N-Benzyloxycarbonyl-1,5-dideoxy-1,5-imino-D-glucitol 
• 19130-96-2 1,5-dideoxy-1,5-imino-D-glucitol 
• 138381-83-6 4,6-O-(R-Benzylidene)-N-benzyloxycarbonyl-1,5-dideoxy-1,5-imino-D-glucitol 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 154865-87-9 (2R,4aR,8S,8aR)-8-Methoxy-7-oxo-2-phenyl-hexahydro-[1,3]dioxino[5,4-b]pyridine-5-carboxylic acid benzyl ester 
• 154865-83-5 (2R,4aR,7S,8R,8aR)-7-Hydroxy-8-methoxy-2-phenyl-hexahydro-[1,3]dioxino[5,4-b]pyridine-5-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

The synthesis of 1,5-dideoxy-1,5-(alkyl)imino-2-C-methyl-D-glucitols

The regio- and stereoselective synthesis of the title compounds 3 and 4 has been accomplished starting with deoxynojirimycin. The factors affecting the stereochemical outcome of Grignard addition to the key carbonyl intermediate are discussed.