1551453-47-4

Basic information

• Product Name: N-(5-(4-ethynylquinolin-6-yl)-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide
• Synonyms: N-(5-(4-ethynylquinolin-6-yl)-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide
• CAS NO: 1551453-47-4
• Molecular Weight: 451.453
• Mol File: 1551453-47-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(5-(4-ethynylquinolin-6-yl)-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-(4-ethynylquinolin-6-yl)-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide(1551453-47-4)
• EPA Substance Registry System: N-(5-(4-ethynylquinolin-6-yl)-2-methoxypyridin-3-yl)-2,4-difluorobenzenesulfonamide(1551453-47-4)

Safety Data

• Hazardous Substances Data: 1551453-47-4(Hazardous Substances Data)

Upstream product

• 1086063-46-8 N-(5-bromo-2-methoxypyridine-3-yl)-2,4-difluorobenzene sulfonyl chloride 
• 1551454-59-1 2,4-difluoro-N-(2-methoxy-5-(4-((trimethylsilyl)ethynyl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide 
• 884495-39-0 5-bromo-2-(methyloxy)-3-pyridinamine 
• 67443-38-3 5-bromo-2-chloro-3-nitropyridine 
• 1086062-75-0 6-bromo-4-chloroquinoline hydrochloride 
• 927801-23-8 6-bromo-4-iodoquinoline 
• 65340-70-7 6-bromo-4-chloroquinoline 
• 152684-30-5 5-bromo-2-methoxy-3-nitropyridine 
• 145369-94-4 6-bromoquinolin-4-ol 
• 106-40-1 4-bromo-aniline 
• 187278-01-9 5-(((4-bromophenyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 1083326-73-1 N-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)-2,4-difluorobenzenesulfonamide 
• 1551454-56-8 6-bromo-4-((trimethylsilyl)ethynyl)quinoline 

Relevant articles and documents

PI3 kinase modulators and methods of use thereof, and use thereof

The invention belongs to the field of medicines, concretely relates to a compound for treating cancer, a composition and an application of the composition and particularly relates to a PI3 kinase regulator as well as a use method and application of the PI3 kinase regulator. The invention provides a compound as shown in the formula (I), a pharmaceutically accepted salt of the compound and a pharmaceutical preparation of the compound, wherein the compound is used for regulating the activity of protein kinase and intercellular or intracellular signal response. The invention also relates to a pharmaceutical composition containing the compound and a method for treating high-proliferative diseases of mammals and particularly human beings by using the pharmaceutical composition as shown in the formula (I).