15517-58-5

Upstream product

• 95-93-2 1,2,4,5-tetramethylbenzene 
• 75-36-5 acetyl chloride 
• 108-24-7 acetic anhydride 
• 488-23-3 1,2,3,4-Tetramethylbenzene 
• 91353-62-7 2,3,5,6-tetramethyl-1-thiomethylbenzene 
• 506-96-7 Acetyl bromide 

Downstream Products

• 67303-54-2 1,2,4,5-tetramethyl-3,6-bis-trichloroacetyl-benzene 
• 100964-21-4 1,4-bis-(1-hydroxy-ethyl)-2,3,5,6-tetramethyl-benzene 
• 95-93-2 1,2,4,5-tetramethylbenzene 
• 2142-79-2 2,3,5,6-tetramethylacetophenone 
• 1183-43-3 1,2,4,5-Tetramethyl-3,6-bis--benzol 
• 1181-99-3 1,2,4,5-Tetramethyl-3,6-bis-<4-carboxy-phenylimino-acetyl>-benzol 
• 100721-30-0 1,4-bis-(1,2-dibromo-ethyl)-2,3,5,6-tetramethyl-benzene 
• 100721-14-0 1,2,4,5-tetramethyl-3,6-divinyl-benzene 
• 97030-75-6 1,2,4,5-Tetramethyl-3,6-di-glyoxyl-benzol 
• 33962-13-9 p-diethyltetramethylbenzene 

Relevant academic research and scientific papers

Transition metal free α-C-alkylation of ketones using secondary alcohols

A base-mediated α-C-alkylation of ketones with secondary alcohols has been developed. This transition metal free approach employs KOt-Bu as the base and exhibits a broad scope, allowing a range of commodity aliphatic secondary alcohols and 1-arylethanols

Hydrogen Borrowing Catalysis with Secondary Alcohols: A New Route for the Generation of β-Branched Carbonyl Compounds

A hydrogen borrowing reaction employing secondary alcohols and Ph? (Me5C6) ketones to give β-branched carbonyl products is described (21 examples). This new C-C bond forming process requires low loadings of [Cp?IrCl2]2, relatively low temperatures, and up to 2.0 equiv of the secondary alcohol. Substrate-induced diastereoselectivity was observed, and this represents the first example of a diastereoselective enolate hydrogen borrowing alkylation. By utilizing the Ph? group, the β-branched products could be straightforwardly cleaved to the corresponding esters or amides using a retro-Friedel-Crafts reaction. Finally, this protocol was applied to the synthesis of fragrance compound (±)-3-methyl-5-phenylpentanol.

NOVEL INITIATORS FOR LIVING CARBOCATIONIC POLYMERIZATION

In various embodiments, the present invention is directed to new low cost initiator compositions for use with the production of well-defined telechelic PIBs (by LC+P of isobutylene). In various other embodiments, the present invention is directed to metho