1552-80-3Relevant academic research and scientific papers
Preparation of 2,2-Dihalocarboxylic Acid Methyl Esters by Oxidation-Chlorination of 2-(1-Haloalkyl)-4-methyl-1,3-dioxolanes with Trichloroisocyanuric Acid
Boni, Monica,Ghelfi, Franco,Pagnoni, Ugo Maria,Zucchi, Claudia
, p. 1622 - 1626 (1994)
Methyl 2,2-dichloro or 2-bromo-2-chloro carboxylates were obtained in excellent yields by oxidation-chlorination of 2-(1-haloalkyl)-4-methyl-1,3-dioxolanes with trichloroisocyanuric acid.
Trichloroisocyanuric Acid Oxidation of 2-Chloro Aldehyde Acetals to 2-Chloro Acids Esters
Boni, Monica,Ghelfi, Franco,Pagnoni, Ugo Maria,Pinetti, Adriano
, p. 156 - 159 (2007/10/02)
2-Chloro acid methyl esters were prepared in good yields treating 2-chloro aldehyde dimethyl acetals with trichloroisocyanuric acid in DMF.Aldehyde dimethyl acetals with the 2-halogen on a tertiary carbon atom were poorly reactive and could be oxidized efficiently only after their transformation into 1,3-dioxolanes.
ELECTROCHEMICAL CROSS-COUPLING OF ORGANIC HALIDES: TRICHLORMETHYLATION AND RELATED SYNTHESIS OF GEM-DICHLORO COMPOUNDS
Nedelec, J. Y.,Ait-Haddou-Mouloud, H.,Folest, J. C.,Perichon, J.
, p. 1699 - 1700 (2007/10/02)
The cross-coupling of activated alkyl halides with carbon tetrachloride or substituted trichloromethanes can be obtained electrochemically in good yield in an undivided cell with a sacrificial anode.
Electrochemical Cross-Coupling of Alkyl Halides in the Presence of a Sacrificial Anode
Nedelec, Jean-Yves,Mouloud, Hassan Ait Haddou,Folest, Jean-Claude,Perichon, Jacques
, p. 4720 - 4724 (2007/10/02)
The electrochemical trichloromethylation of various alkyl halides has been obtained in high yields in an undivided cell in the presence of a sacrificial anode.This cross-coupling process has been extended to the preparation of numerous gem-dichloro compounds from trichloro-substituted methanes and alkyl halides.Zinc,magnesium or aluminium were used as anodes according to the reduction potentiel of the reagents.Mixtures of polar aprotic solvents,e.g.THF-TMU or THF-NMP, were found more appropriate than pure solvents.The critical role of the metallic ions from the consumption of the anode has been clearly evidenced.
