155295-58-2

Upstream product

• 20312-36-1 L-3-phenyllactic acid 
• 123394-79-6 (S)-2-(benzyloxy)-1-hydroxy-3-phenylpropane 
• 118535-75-4 (2S)-2-benzyloxy-3-phenylpropanal 

Downstream Products

• 125225-52-7 (5S,1'S)-5-(1'-hydroxy-2'-phenylethyl)dihydrofuran-2(3H)-one 
• 220588-83-0 5(S)-[1(S)-[(tert-butyldimethylsilyl)oxy]-2-phenylethyl]dihydrofuran-2(3H)-one 
• 155295-60-6 5(S)-[1(S)-benzyloxy-2-phenylethyl]-3(R)-(cyclopropylmethyl)dihydrofuran-2(3H)-one 
• 220588-84-1 5(S)-[2-phenyl-1(S)-[(tert-butyldimethylsilyl)oxy]ethyl]-3(S)-(2-thienylmethyl)dihydrofuran-2(3H)-one 
• 220589-05-9 (2S,4S,5S)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-6-phenyl-2-thiophen-2-ylmethyl-hexanoic acid 
• 155295-62-8 N-[1(S)-(cyclohexylmethyl)-2(R),3(S)-dihydroxy-5-methylhexyl]-2(R)-(cyclopropylmethyl)-5(S)-benzyloxy-4(S)-hydroxy-6-phenylhexanamide 
• 155295-61-7 N-[1(S)-(cyclohexylmethyl)-2(R),3(S)-dihydroxy-5-methylhexyl]-5(S)-benzyloxy-4(S)-[(tert-butyldimethylsilyl)oxy]-2(R)-(cyclopropylmethyl)-6-phenylhexanamide 
• 220588-85-2 4(S),5(S)-bis[(tert-butyldimethylsilyl)oxy]-N-[1(S)-(cyclohexylmethyl)-2(R),3(S)-dihydroxy-5-methylhexyl]-6-phenyl-2(S)-(2-thienylmethyl)hexanamide 
• 155295-59-3 5(S)-[1(S)-benzyloxy-2-phenylethyl]-3(R)-(2-propenyl)dihydrofuran-2(3H)-one 

Relevant academic research and scientific papers

Novel small renin inhibitors containing 4,5- or 3,5-Dihydroxy-2-substituted-6-phenylhexanamide replacements at the P2-P3 sites

Renin inhibitors containing a 4,5- or a 3,5-dihydroxy-2-substituted-6-phenylhexanamide fragment at the P2-P3 sites have been prepared and evaluated. The four possible diastereomeric diols of the two series of inhibitors were synthesi