155322-26-2

Basic information

• Product Name: norchloroepibatidine
• Synonyms: norchloroepibatidine
• CAS NO: 155322-26-2
• Molecular Formula: C11H14N2
• Molecular Weight: 174.24226
• Mol File: 155322-26-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 305.8°Cat760mmHg
• Flash Point: 138.8°C
• Appearance: /
• Density: 1.098g/cm³
• Vapor Pressure: 0.000801mmHg at 25°C
• Refractive Index: 1.564
• CAS DataBase Reference: norchloroepibatidine(CAS DataBase Reference)
• NIST Chemistry Reference: norchloroepibatidine(155322-26-2)
• EPA Substance Registry System: norchloroepibatidine(155322-26-2)

Safety Data

• Hazardous Substances Data: 155322-26-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14N2/c1-2-8(7-12-5-1)10-6-9-3-4-11(10)13-9/h1-2,5,7,9-11,13H,3-4,6H2/t9-,10+,11+/m0/s1

Upstream product

• 153400-52-3 7-carbomethoxy-7-azabicyclo<2.2.1>hept-2-ene 
• 1120-90-7 3-iodopyridine 
• 151885-31-3 (Z)-3-(6-Chloro-pyridin-3-yl)-acrylic acid methyl ester 
• 21543-49-7 2-Chloro-5-hydroxymethylpyridine 
• 23100-12-1 6-chloronicotinylaldehyde 
• 5326-23-8 6-Chloro-3-pyridinecarboxylic acid 
• 151885-38-0 2,2,2-Trifluoro-1-((1R,2R,4S)-2-pyridin-3-yl-7-aza-bicyclo[2.2.1]hept-7-yl)-ethanone 
• 152004-92-7 N-[(1R,2R,4S,5S)-4,5-Dibromo-2-(6-chloro-pyridin-3-yl)-cyclohexyl]-2,2,2-trifluoro-acetamide 
• 152004-91-6 N-[(1R,6R)-6-(6-Chloro-pyridin-3-yl)-cyclohex-3-enyl]-2,2,2-trifluoro-acetamide 
• 151885-37-9 2,2,2-Trifluoro-1-[(1R,2R,4S)-2-(6-iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]hept-7-yl]-ethanone 
• 152004-93-8 (+)-N-(Trifluoroacetyl)epibatidine 

Relevant articles and documents

Synthesis and [11C]-radiolabelling of dechloro-epibatidine and 2PABH, two potential radioligands for studying the central nAChRs in vivo

The two epibatidine (EPB) analogues dechloro-epibatidine (DCl-EPB) and 2PABH were synthesised via a two step reaction starting from N-methoxycarbonyl-7-azabicyclo[2.2.1]heptene. The radiochemical syntheses of [11C]N-methylated derivatives was performed using the classical methylating agent [11C]CH3I in acetonitrile. The radiochemical yield ranged from 5 to 10% (decay corrected from [11C]CH3I) and was fully sufficient for small animal experiments. High specific activities in the range of 140 to 360 GBq/μmol at EOS (end of synthesis) were obtained. The radiosynthesis, semipreparative HPLC, formulation and quality control were completed in an average time of 35 min.