1554-59-2

Basic information

• Product Name: 2-Thiazolamine, N,4-bis(4-fluorophenyl)-
• CAS NO: 1554-59-2
• Molecular Formula: C15H10F2N2S
• Molecular Weight: 288.321
• Mol File: 1554-59-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 110 °C
• Boiling Point: 421.7±55.0 °C(Predicted)
• Density: 1.360±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-Thiazolamine, N,4-bis(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiazolamine, N,4-bis(4-fluorophenyl)-(1554-59-2)
• EPA Substance Registry System: 2-Thiazolamine, N,4-bis(4-fluorophenyl)-(1554-59-2)

Safety Data

• Hazardous Substances Data: 1554-59-2(Hazardous Substances Data)

Upstream product

• 371-40-4 4-fluoroaniline 
• 43045-16-5 1-(4-fluorophenyl)-2-thiocyanatoethan-1-one 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 357952-79-5 1-(4-fluorophenyl)-2-(p-tolylsulfonyloxy)ethanone 
• 459-05-2 (4-fluoro-phenyl)-thiourea 
• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 399-07-5 N-((4-fluorophenyl)carbamothioyl)benzamide 

Relevant articles and documents

A Small Molecule Mimetic of the Humanin Peptide as a Candidate for Modulating NMDA-Induced Neurotoxicity

Humanin (HN), a 24-amino acid bioactive peptide, has been shown to increase cell survival of neurons after exposure to Aβ and NMDA-induced toxicity and thus could be beneficial in the treatment of Alzheimer's disease (AD). The neuroprotection by HN is rep

SUBSTITUTED 4-ARYLTHIAZOLES AND PROCESS OF PREPARATION THEREOF

The present invention relates to novel substituted 4-arylthiazoles, their preparation, and to their use as therapeutic agents, particularly in the prevention or treatment of tuberculosis. The resent invention articularl relates to com ounds of formula A:

Organoiodine(III) mediated one-pot synthesis of N-substituted 2-aminothiazoles

The synthesis of N-substituted 2-aminothiazoles has been achieved in one-pot by the successive treatment of acetophenones with [hydroxy(tosyloxy) iodo)benzene (HTIB), potassium thiocyanate and appropriate aniline.