15541-26-1

Basic information

• Product Name: 1-(2-METHOXYPHENYL)-2-PROPANOL 98
• Synonyms: 1-(2-METHOXYPHENYL)-2-PROPANOL 98;1-(2-METHOXYPHENYL)-2-PROPANOL 98%;1-(2-methoxyphenyl)propan-2-ol
• CAS NO: 15541-26-1
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.21696
• Mol File: 15541-26-1.mol
• Article Data: 6

Chemical Properties

• Flash Point: >230 °F
• Appearance: /
• Density: 1.035 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.529(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(2-METHOXYPHENYL)-2-PROPANOL 98(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-METHOXYPHENYL)-2-PROPANOL 98(15541-26-1)
• EPA Substance Registry System: 1-(2-METHOXYPHENYL)-2-PROPANOL 98(15541-26-1)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 15541-26-1(Hazardous Substances Data)

Usage

General Description

1-(2-Methoxyphenyl)-2-propanol 98 is a chemical compound with the molecular formula C10H14O2. It is a colorless liquid with a slightly floral odor, and it is commonly used as a fragrance ingredient in cosmetic and personal care products. This chemical is also used in the production of pharmaceuticals and can act as a solvent or intermediate in organic synthesis. It has a purity of 98% and is typically stored in a cool, dry place away from direct sunlight and incompatible materials. Safety precautions should be taken when handling this chemical, including wearing appropriate protective gear and following proper handling and disposal procedures.

Upstream product

• 578-57-4 2-bromoanisole 
• 75-56-9 methyloxirane 
• 3698-28-0 2-allylanisole 
• 100-66-3 methoxybenzene 
• 5211-62-1 1-(2-methoxyphenyl)propan-2-one 

Downstream Products

• 65725-90-8 1-(2-methoxyphenyl)propan-2-yl acetate 

Relevant articles and documents

Markovnikov Wacker-Tsuji Oxidation of Allyl(hetero)arenes and Application in a One-Pot Photo-Metal-Biocatalytic Approach to Enantioenriched Amines and Alcohols

The Wacker-Tsuji aerobic oxidation of various allyl(hetero)arenes under photocatalytic conditions to form the corresponding methyl ketones is presented. By using a palladium complex [PdCl2(MeCN)2] and the photosensitizer [Acr-Mes]ClO4 in aqueous medium and at room temperature, and by simple irradiation with blue led light, the desired carbonyl compounds were synthesized with high conversions (>80%) and excellent selectivities (>90%). The key process was the transient formation of Pd nanoparticles that can activate oxygen, thus recycling the Pd(II) species necessary in the Wacker oxidative reaction. While light irradiation was strictly mandatory, the addition of the photocatalyst improved the reaction selectivity, due to the formation of the starting allyl(hetero)arene from some of the obtained by-products, thus entering back in the Wacker-Tsuji catalytic cycle. Once optimized, the oxidation reaction was combined in a one-pot two-step sequential protocol with an enzymatic transformation. Depending on the biocatalyst employed, i. e. an amine transaminase or an alcohol dehydrogenase, the corresponding (R)- and (S)-1-arylpropan-2-amines or 1-arylpropan-2-ols, respectively, could be synthesized in most cases with high yields (>70%) and in enantiopure form. Finally, an application of this photo-metal-biocatalytic strategy has been demonstrated in order to get access in a straightforward manner to selegiline, an anti-Parkinson drug. (Figure presented.).

Ortho-directed functionalization of arenes using magnesate bases

Ortho-directed functionalisation of arenes using lithium alkylmagnesate bases were achieved, demonstrating the potential use of arylmagnesates as suitable arylanions, without a further transmetallation step, for challenging functionalizations such as fluorination, hydroxylation, arylation, vinylation and alkylation through epoxide ring-opening.

Novel photohydration of non-conjugated aryl/olefin bichromophores within cyclodextrin cavities

Cyclodextrin media are used to achieve photochemical water addition to isolated, acyclic double bonds via intramolecular interaction with excited arenes.