155591-00-7

Upstream product

• 71516-40-0 4-(cyanomethyl)-1-(p-toluenesulfonyl)indole 
• 92573-18-7 ethyl 1-{[(4-methylphenyl)sulfonyl]-1H-indol-4-yl}acetate 

Downstream Products

• 1027843-58-8 [1-(Toluene-4-sulfonyl)-1H-indol-4-yl]-acetyl chloride 
• 155591-01-8 3-(p-toluenesulfonyl)-6,7,8,9-tetrahydro-3H-benzindol-8-one 
• 1018452-12-4 2,2-dimethyl-5-(2-(1-tosyl-1H-indol-4-yl)ethyl)-1,3-dioxane-4,6-dione 

Relevant academic research and scientific papers

Synthesis of fused 4,5-disubstituted indole ring systems by intramolecular friedel-crafts acylation of 4-substituted indoles

(Chemical Equation Presented) 4-Substituted indoles containing a variety of electrophiles and N-substituents undergo Friedel-Crafts acylation to give exclusively the products of cyclization at the 5-position of indole. These indanones and tetralones have been scarcely prepared and are subunits in natural products and analogues of potential biological significance.

Sulfonyltetrahydro-3H-benzo(E)indole-8-amine compounds as 5-Hydroxytryptamine-6 ligands

The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of a CNS disorder related to or affected by the 5-HT6 receptor.

Synthesis of (R)- and (S)-1-formyl-6,7,8,9-tetrahydro-N,N-(dipropyl)-3H- benz[e]indol-8-amines: Potent and orally active 5-HT(1A) receptor agonists

An efficient synthesis of the potent and orally active 5-HT(1A) agonists, (R)-(+)- and (S)-(-)-l-formyl-6,7,8,9-tetrahydro-N,N-dipropyl-3H- benz[e]indol-8-amines 1a and 1b, is described. This synthesis was accomplished in twelve steps from commercially av