155632-06-7

Basic information

• Product Name: 2,4-Pyrimidinediol, 6-methyl-, dibenzoate (ester)
• CAS NO: 155632-06-7
• Molecular Formula: C19H14N2O4
• Molecular Weight: 334.331
• Mol File: 155632-06-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,4-Pyrimidinediol, 6-methyl-, dibenzoate (ester)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Pyrimidinediol, 6-methyl-, dibenzoate (ester)(155632-06-7)
• EPA Substance Registry System: 2,4-Pyrimidinediol, 6-methyl-, dibenzoate (ester)(155632-06-7)

Safety Data

• Hazardous Substances Data: 155632-06-7(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 626-48-2 2,4-dihydroxy-6-methylpyrimidine 
• 626-48-2 6-Methyluracil 

Downstream Products

• 582-62-7 3-methyl-1-phenylbutan-1-one 
• 18998-78-2 1-phenyl-hept-2-yn-1-one 
• 954-16-5 2,4,6-Trimethylbenzophenon 
• 626-48-2 6-Methyluracil 
• 136-60-7 benzoic acid, butyl ester 
• 120-51-4 benzoic acid benzyl ester 
• 155632-07-8 1,3-dibenzoyl-6-methyluracil 
• 93-98-1 N-phenyl benzoyl amide 
• 2782-40-3 N-butylbenzamide 
• 1696-17-9 N,N-diethylbenzamide 
• 884-09-3 phenyl thiobenzoate 
• 18838-10-3 N-(2-hydroxyethyl)-benzamide 
• 19811-56-4 hippuric acid tert-butyl ester 
• 102877-79-2 N-(4-hydroxybutyl)benzamide 

Relevant articles and documents

6-methyl-2, 4-pyrimidyl diesters. A highly efficient acylating agent for the synthesis of unsymmetrical ketones

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Research on antiviral agents. 4. Studies on the chemistry of 6-methyl-2-methoxy-4-O-acyloxy and 6-methyl-2,4-di-O-acyloxypyrimidine derivatives as new acylation reagents and inhibitors of uracil DNA glycosylases.

The synthesis of 6-methyl-2-methoxy-4-O-acyloxy and 6-methyl-2,4-di-O-acyloxypyrimidine derivatives 2 and 5 along with their properties as acylating agents of amines, alcohols, thiols and α-amino acids have been reported. Interestingly some of the title products revealed an inhibitory activity against the human and herpetic DNA glycosylases.