155983-56-5

Upstream product

• 16836-95-6 silver(I) 4-methylbenzenesulfonate 
• 124750-51-2 N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole 
• 2403-54-5 2-(4-chlorophenyl)-1,3-dioxolane 
• 873-32-5 2-Chlorobenzonitrile 
• 400747-06-0 C₁₆H₁₃O₂N 
• 154709-17-8 5-<2-<4'-(acetoxymethyl)biphenylyl>>-2-(triphenylmethyl)-2H-tetrazole 
• 154709-18-9 4'-hydroxymethyl-2-(N-trityl-1H-tetrazol-5-yl)biphenyl 

Downstream Products

• 138804-30-5 2-methyl-4-<1-<2'-(1H-tetrazol-5-yl)biphenyl-4-yl>ethoxy>quinoline hydrochloride 
• 154709-18-9 4'-hydroxymethyl-2-(N-trityl-1H-tetrazol-5-yl)biphenyl 
• 124750-51-2 N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole 
• 144690-33-5 ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-({2'-[1-(triphenylmethyl)-1H-1,2,3,4-tetrazol-5-yl]-[1,1'-biphenyl]-4-yl}methyl)-1H-imidazole-5-carboxylate 
• 1114761-92-0 lithium 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{4-[2-(trityltetrazol-5-yl)phenyl]phenyl}methylimidazole-5-carboxylate 
• 144690-92-6 trityl olmesartan medoxomil 
• 144689-63-4 olmesartan medoxomil 
• 155983-43-0 (S) N-butyryl-N-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-phenylalanine 

Relevant academic research and scientific papers

A process for the preparation of olmesartan

The invention discloses a preparation method of Olmesartan Medoxomil. The method is used for synthesizing an important intermediate 4-[2-(2-triphenylmethyl tetrazole-5-yl) phenyl] benzyl bromide (a compound III) so as to prepare the compound Olmesartan Medoxomil. The method is high in yield, easy to separate and purify, simple to operate and suitable for industrial production.

Improved Sommelet reaction catalysed by lanthanum triflate

An improved Sommelet reaction for the synthesis of araldehydes from benzyl halides and hexamethylenetetramine was achieved employing lanthanum triflate (3 mol%) as catalyst in water with sodium dodecyl sulfate (SDS, 2 wt%) as solubiliser. Good to excellent yields were obtained in most of the 18 examples.

Angiotensin II receptor blocking tertiary amides

Novel substituted tertiary amides of formula (I), which are useful as angiotensin II antagonists, are disclosed: STR1

New nonpeptide angiotensin II receptor antagonists. 2. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4- (biphenylylmethoxy)quinoline derivatives

A novel series of nonpeptidic angiotensin II (AII) receptor antagonists is reported, derived from linkage of the biphenylcarboxylic acid or biphenylyltetrazole moiety found in previously described antagonists via a methyleneoxy chain to the 4-position of