156017-42-4

Basic information

• Product Name: L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-iodo-, methyl ester
• CAS NO: 156017-42-4
• Molecular Formula: C19H18INO4
• Molecular Weight: 451.261
• Mol File: 156017-42-4.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-iodo-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-iodo-, methyl ester(156017-42-4)
• EPA Substance Registry System: L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-iodo-, methyl ester(156017-42-4)

Safety Data

• Hazardous Substances Data: 156017-42-4(Hazardous Substances Data)

Usage

General Description

L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-iodo-, methyl ester is a chemical compound that consists of L-Alanine, a non-essential amino acid, and a fluorenylmethoxycarbonyl (Fmoc) protecting group attached to a methyl ester. The presence of the 3-iodo group makes this compound potentially useful in synthetic chemistry as a building block for constructing more complex molecules. The Fmoc protecting group is commonly used in peptide synthesis to protect the amine group of amino acids, allowing for selective deprotection and subsequent chemical reactions. L-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-iodo-, methyl ester has potential applications in the fields of biochemistry, pharmaceuticals, and organic synthesis.

Upstream product

• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 
• 73724-45-5 N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine 
• 82911-78-2 N-[(9-fluorenylmethoxy)carbonyl]-L-serine methyl ester 
• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 229962-91-8 methyl (2S)-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)-3-(((4-methylbenzene)sulfonyl)oxy)propanoate 

Downstream Products

• 150308-80-8 N-(9-fluorenylmethoxycarbonyl)-Se-(p-methoxyphenylmethyl)-L-selenocysteine 
• 1365284-58-7 Fmoc-Sec(Mob)-OMe 
• 1360157-23-8 (S)-methyl-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-(N,N-bis(2,4-dimethoxybenzyl)sulfamoyl)-1-trityl-1H-imidazol-2-yl)propanoate 
• 156017-45-7 (S)-2-{[(9H-fluoren-9-yl)methoxy]carbonylamino}-3-{4-[(diethoxyphosphoryl)difluoromethyl]phenyl}propanoic acid 
• 282734-37-6 (2S)-2-(fluorenylmethoxycarbonylamino)-3-(5'-bromo-2'-pyridyl)propionic acid 
• 185379-40-2 (2S)-(N-fluorenylmethoxycarbonylamino)-3-(pyrid-2'-yl)propionic acid 
• 156017-44-6 Fmoc-(4-diethyl phosphonodifluoromethyl)-Phe-OMe 

Relevant articles and documents

Crystal (6S,9aS)-N-benzyl-8-({6-[3-(4-ethylpiperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-6-(2-fluoro-4-hydroxybenzyl)-4,7-dioxo-2-(prop-2-en-1-yl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide

The present invention provides a crystal of (6S,9aS)-N-benzyl-8-({6-[3-4-ethylpiperazin-1-yl)azetidin-1-yl]pyridin-2-yl} methyl)-6-(2-fluoro-4-hydroxybenzyl)-4,7-dioxo-2-(prop-2-en-1-yl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide.

(6S,9aS)-N-Benzyl-6-[(4-hydroxyphenyl)methyl]-4,7-dioxo-8-(methyl)-2-(prop-2-en-1-yl)-octahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide compound

A compound represented by formula (1) or pharmaceutically acceptable salt thereof: wherein R1 is a C1-6 alkyl group; R2 and R3 are the same or different from each other and each is a hydrogen atom or a C1-6 alkyl group; X2, X3 and X4 are the same or different from each other and each is a hydrogen atom or a halogen atom; and X5 is a hydrogen atom or —P(═O)(OH)2 has a Wnt Pathway modulating activity.

Synthesis of chiral Nβ-protected amino diselenides from the corresponding amino alkyl iodides using NaBH2Se3 as a selenating reagent and their conversion to seleninic acids

A convenient approach has been presented for the synthesis of Nβ-protected amino diselenides from the corresponding amino alkyl iodides using in situ generated NaBH2Se3 as an efficient selenating reagent. All the diselenid