20264-95-3

Basic information

• Product Name: 1-CHLORO-2-(4-NITROPHENYL)ETHANE
• Synonyms: 1-CHLORO-2-(4-NITROPHENYL)ETHANE;4-(2-Chloroethyl)nitrobenzene;NSC 143402 1-(2-Chloroethyl)-4-nitrobenzene
• CAS NO: 20264-95-3
• Molecular Formula: C₈H₈ClNO₂
• Molecular Weight: 185.61
• Mol File: 20264-95-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 171℃
• Boiling Point: 307.5°C at 760 mmHg
• Flash Point: 139.8°C
• Appearance: /
• Density: 1.275g/cm³
• Vapor Pressure: 0.00131mmHg at 25°C
• Refractive Index: 1.562
• CAS DataBase Reference: 1-CHLORO-2-(4-NITROPHENYL)ETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLORO-2-(4-NITROPHENYL)ETHANE(20264-95-3)
• EPA Substance Registry System: 1-CHLORO-2-(4-NITROPHENYL)ETHANE(20264-95-3)

Safety Data

• Hazardous Substances Data: 20264-95-3(Hazardous Substances Data)

Usage

General Description

1-CHLORO-2-(4-NITROPHENYL)ETHANE is a chemical compound with the molecular formula C8H7ClNO2. It is a chlorinated ether that contains a nitrophenyl group, which is often used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. This chemical compound is commonly used in organic synthesis and research laboratories for its ability to undergo various chemical reactions, including nucleophilic substitution and aromatic nitration. It is also known for its potential use as an insect repellent and antifungal agent. However, it is important to handle this compound with caution as it is considered to be toxic and may cause irritation to the skin, eyes, and respiratory system. Therefore, it should be handled in a well-ventilated area and with appropriate personal protective equipment.

InChI:InChI=1/C8H8ClNO2/c9-6-5-7-1-3-8(4-2-7)10(11)12/h1-4H,5-6H2

Upstream product

• 74-85-1 ethene 
• 100-05-0 4-nitrobenzenediazonium chloride 
• 100-27-6 2-(4-nitrophenyl)ethanol 
• 622-24-2 2-phenylethyl chloride 
• 64-04-0 phenethylamine 
• 98-07-7 Benzotrichlorid 
• 59457-26-0 1-chloro-1λ³-benzo[d][1,2]iodaoxol-3(1H)-one 
• 7664-93-9 sulfuric acid 
• 7697-37-2 nitric acid 
• 60-12-8 2-phenylethanol 

Downstream Products

• 210158-20-6 4-[2-(4-nitro-phenyl)-ethyl]-morpholine 
• 92191-78-1 4-(4-nitro-phenethylamino)-phenol 
• 80259-15-0 2-(4-nitro-phenyl)ethanesulfonyl chloride 
• 110274-67-4 S-(4-nitro-phenethyl)-isothiourea; hydrochloride 
• 102882-57-5 N-methyl-N-(4-nitro-phenethyl)-p-anisidine 
• 14310-29-3 1-nitro-4-phenethylbenzene 
• 108787-34-4 bis(N,N-diisopropylamino)-2-(4-nitrophenyl)ethoxyphosphane 
• 5339-24-2 4-<2-(N,N-di-n-propylamino)ethyl>-nitrobenzene 
• 81865-10-3 2-(4-aminophenyl)ethyl chloride 
• 104-30-3 2-(4-nitrophenyl)ethyl acetate 
• 62-23-7 4-nitro-benzoic acid 
• 302516-76-3 4-[2-[N-methyl-N-(4-isopropoxyphenyl)amino]ethyl]-1-[2-(4-nitrophenyl)ethyl]piperidin-4-ol 
• 1391611-28-1 C₂₂H₁₇N₃O₃ 
• 1391611-31-6 C₂₂H₁₇N₃O₃ 

Relevant articles and documents

Organocatalytic Chlorination of Alcohols by P(III)/P(V) Redox Cycling

A catalytic system for the chlorination of alcohols under Appel conditions was developed. Benzotrichloride is used as a cheap and readily available chlorinating agent in combination with trioctylphosphane as the catalyst and phenylsilane as the terminal reductant. The reaction has several advantages over other variants of the Appel reaction, e.g., no additional solvent is required and the phosphane reagent is used only in catalytic amounts. In total, 27 different primary, secondary, and tertiary alkyl chlorides were synthesized in yields up to 95%. Under optimized conditions, it was also possible to convert epoxides and an oxetane to the dichlorinated products.

HETEROCYCLIC SUBSTITUTED PIPERAZINES FOR THE TREATMENT OF SCHIZOPHRENIA

This invention relates to compounds of the formula 1 wherein X, Y, Z, A, R', R2, R3, R4, R9, W' and W2 are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system and other diso

Nucleotides. Part XL. Synthesis and characterization of modified 2'-5' adenylate trimers - Potential antiviral agents

2'-5' Adenylate trimers 41-44 carrying the (tert-butyl)dimethylsilyl (tbds) group at the 3'-OH position of various sugar moieties were synthesized via the phosphoramidite method. The use of the (tert-butyloxy)carbony (boc) and (2-(4-nitrophenyl)ethylsulfo