15622-65-8 Usage
Chemical Properties
Light Tan Solid
Originator
Moban,Endo,US,1974
Uses
Different sources of media describe the Uses of 15622-65-8 differently. You can refer to the following data:
1. D2 Dopamine receptor antagonist. MAO inhibitor. Antipsychotic.
2. Antipsychotic;Dopamine receptor antagonist
Manufacturing Process
Diethyl ketone may be reacted with methyl nitrite and that product in turn reacted with cyclohexan-1,3-dione to give 3-ethyl-4,5,6,7-tetrahydro-2-
methyl-4-oxoindole.3-ethyl-4,5,6,7-tetrahydro-2-methyl-4-oxoindole 14.1 g (0.08 mol), 14.8 g
morpholine hydrochloride (0.12 mol), and 3.6 g paraformaldehyde (0.12 mol)
were refluxed in 200 ml ethanol for 40 hours. The solution was evaporated to
dryness in vacuo on a steam bath and the residue digested with a mixture of
150 ml water and 10 ml 2N HCl. An insoluble residue of unreacted starting
material was filtered off. To the acid solution, ammonia water was added
dropwise with stirring and the amine crystallized out. It was purified by
dissolving in 1N HCl and addition of ammonia, then by 2 crystallizations from
benzene followed by 2 crystallizations from isopropanol, to yield 3-ethyl-
4,5,6,7-tetrahydro-2-methyl-4-oxoindole, melting point 180°C to 181°C.
Brand name
Moban (Endo).
Therapeutic Function
Antipsychotic
Check Digit Verification of cas no
The CAS Registry Mumber 15622-65-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,6,2 and 2 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15622-65:
(7*1)+(6*5)+(5*6)+(4*2)+(3*2)+(2*6)+(1*5)=98
98 % 10 = 8
So 15622-65-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H24N2O2.ClH/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18;/h12,17H,3-10H2,1-2H3;1H
15622-65-8Relevant articles and documents
PROCESS FOR PREPARATION OF MOLINDONE
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, (2020/08/30)
The present invention provides process for preparation of molindone (I) comprising: a) reacting compound with cyclohexane-1,3-dione to form 2-(2-oxopentan-3-yl)cyclohexane-1,3-dione wherein X is Cl, Br or I, b) cyclizing 2-(2-oxopentan-3-yl)cyclohexane-1,