815-48-5

Upstream product

• 107-87-9 2-Pentanone 
• 7732-18-5 water 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 

Downstream Products

• 19013-49-1 2-ethyl-3-methylindole 
• 816-21-7 1,3-dibromo-pentan-2-one 
• 2648-70-6 3,3-dibromo-pentan-2-one 
• 21241-68-9 2-(4-dimethylamino-phenyl)-5-ethyl-3,4-dimethyl-thiazolium; iodide 
• 96428-73-8 8-Benzyloxy-3-ethyl-2-methyl-imidazo[1,2-a]pyridine 
• 710325-44-3 3-phenylaminopentan-2-one 
• 92801-74-6 (iodo-1 propyl)-2 methyl-2 dioxolanne-1,3 
• 17649-45-5 3-Benzylamino-pentan-2-on 
• 6116-76-3 3-ethyl-2-methyl-4-oxo-1H-4,5,6,7-tetrahydroindole 
• 15622-65-8 molindone hydrochloride 
• 80079-25-0 2-ethyl-3-methylbenzofuran 
• 91496-88-7 3-Benzoyloxy-pentanon-⁽²⁾ 

Relevant academic research and scientific papers

AMBER ODORANT

The present invention concerns compound of formula (I) in the form of any one of its stereoisomers or as a mixture thereof, and wherein Q group represents a —CH=CH—CH3 group or a —C≡C—CH3 group. The use as a perfuming ingredient of the invention's compound and the invention's compound as part of a perfuming composition or of a perfuming consumer product are also part of the present invention.

METALLOENZYME INHIBITOR COMPOUNDS

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

CXCR4 Receptor Antagonists

Disclosed are compounds that are antagonists of the CXCR4 receptor.

CXCR4 RECEPTOR ANTAGONISTS

The compounds of formula (I) are antagonists of the CXCR4 receptor Wherein R1, X, Y and R2 are as defined in the claims.

Studies of nonnucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Design and synthesis of thiazolidenebenzenesulfonamides

A series of thiazolidenebenzenesulfonamides have been discovered as nonnucleoside reverse transcriptase inhibitors. Compound 17a exhibited the most potent inhibitory activity against the Y181C mutant reverse transcriptase (RT). The introduction of the 4-c

A mild and efficient procedure for α-bromination of ketones using N-bromosuccinimide catalysed by ammonium acetate

Cyclic ketones reacted with N-bromosuccinimide (NBS) catalysed by NH 4OAc in Et2O at 25°C to give the corresponding α-brominated ketones in good yields, while acyclic ketones were efficiently brominated in CCl4 at 80°C.

Regiospecific synthesis of unsymmetrical α-bromoketones

A convenient regiospecific preparation of unsymmetrical α-bromoketones, commencing from Meldrum's acid, has been developed. This procedure allows for preparation of α-bromoketones which are unobtainable in a pure state by other bromination methods and is

Selective bromination of ketones. A convenient synthesis of 5-aminolevulinic acid

Bromination of unsymmetrical ketones with Br2 in methanol proceeded regioselectively in good yield at the less substituted methyl carbon. The bromination of levulinic acid using this method was followed by azidation and amination to lead to an efficient three-step synthesis of 5-aminolevulinic acid in 36% overall yield.

Synthesis of three retinal models, including the 10-s-cis-locked retinal, all-E-12,19-methanoretinal

All-E-12,19-methanoretinal (1) is distinguished by the presence of the locked 10-s-cis conformation in the cyclohexadiene ring in the conjugated chain. 1 has been prepared together with its 13-Z isomer in an overall yield of 0.5percent. 1 and 13-Z-1 photochemically interconvert in a clean way.In this system, only photoisomerization around the C13=C14 double bond is observed.In the photostationary state, the 13-Z isomer is predominant.All-E-12-ethyl-19-methylretinal (2) and all-E-12-ethylretinal (3) were prepared in good overall yields (20percent and 30percent) from β-ionone using the novel synthon, 3-methyl-4-(diethylphosphono)-2-hexenenitrile (11).The photochemistry of these retinal derivatives is very similar to that of retinal.The 9-Z, 11-Z and 13Z isomers of 2 and 3 were photochemically prepared.The 13C NMR spectra of these new compounds gave information about the structural elements of alkyl groups in conjugated systems and about the conformation of the conjugated chain.