156463-85-3

Basic information

• Product Name: 1,2,5-Oxadiazole-3-carbonitrile,4-amino-(9CI)
• Synonyms: 1,2,5-Oxadiazole-3-carbonitrile,4-amino-(9CI);4-Aminofurazan-3-carbonitrile, 3-Amino-4-cyano-1,2,5-oxadiazole;4-aminofurazan-3-carbonitrile;1,2,5-Oxadiazole-3-carbonitrile,4-amino-
• CAS NO: 156463-85-3
• Molecular Formula: C₃H₂N₄O
• Molecular Weight: 110.076
• Product Categories: NITRILE
• Mol File: 156463-85-3.mol
• Article Data: 19

Chemical Properties

• Melting Point: 85-87 °C
• Boiling Point: 354.5±52.0 °C(Predicted)
• Appearance: /
• Density: 1.54±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: -2.53±0.10(Predicted)
• CAS DataBase Reference: 1,2,5-Oxadiazole-3-carbonitrile,4-amino-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,5-Oxadiazole-3-carbonitrile,4-amino-(9CI)(156463-85-3)
• EPA Substance Registry System: 1,2,5-Oxadiazole-3-carbonitrile,4-amino-(9CI)(156463-85-3)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 156463-85-3(Hazardous Substances Data)

Usage

Chemical Properties

White crystal

Upstream product

• 540-61-4 2-aminoacetonitrile 
• 13300-88-4 4-amino-1,2,5-oxadiazole-3-carboxylic acid amide 
• 1211025-52-3 4-amino-N’-hydroxy-1,2,5-oxadiazole-3-carboximidamide 
• 13490-32-9 4-amino-N-hydroxy-furazan-3-carboxamidine 
• 1211025-52-3 4-amino-N-hydroxyfurazan-3-carboxamidine 
• 13490-32-9 amidoxime of 4-aminofurazan-3-carboxylic acid 

Downstream Products

• 13490-32-9 4-amino-N-hydroxy-furazan-3-carboxamidine 
• 167281-92-7 4-aminofurazan-3-carboxamidrazone 
• 246048-63-5 methyl 4-amino-1,2,5-oxadiazolyl-3-carbimidate 
• 696631-99-9 methyl 7-amino-5-methyl[1,2,5]oxadiazolo[3,4-b]pyridine-6-carboxylate 
• 159014-14-9 4-nitro-1,2,5-oxadiazole-3-carbonitrile 
• 1279684-99-9 2-chloro-3-[5-(cyanomethyl)-4,5-dihydro-1,2-oxazol-3-yl]-N-(4-cyano-1,2,5-oxadiazol-3-yl)-4-(ethylsulfonyl)benzamide 
• 167281-96-1 3-amino-4-(1,2,3,4-tetrazol-5-yl)furazan 

Relevant articles and documents

Synthesis and properties of 3-azido-4-(2H-tetrazol-5-yl)furazan

[Figure not available: see fulltext.] We describe an effective scheme for the synthesis of a new energetic compound – 3-azido-4-(2H-tetrazol-5-yl)furazan from 4-amino-N'-hydroxyfurazan-3-carboximidamide. The structure of 3-azido-4-(2H-tetrazol-5-yl)furazan was proved by 1Н and 13С NMR spectroscopy, mass spectrometry, and X-ray structural analysis. 3-Azido-4-(2H-tetrazol-5-yl)furazan crystallized in monoclinic syngony, space group Р21/n, monocrystal density d 1.953 g·cm–3 (100 K). According to differential scanning calorimetry data, 3-azido-4-(2Htetrazol-5-yl)furazan melts at 103.3°С, while the maximum of thermal decomposition exotherm was observed at 185.6°С. The sensitivity of 3-azido-4-(2H-tetrazol-5-yl)furazan to impact (2 kg, 25 cm, 36% explosion frequency) and to friction (1450 kg·cm–3 lower limit) was at the level of pentaerythritol tetranitrate. The salts of 3-azido-4-(2H-tetrazol-5-yl)furazan with ammonia and guanylurea were also obtained and characterized.

PROCESS FOR MANUFACTURING ALKYL 7-AMINO-5-METHYL- [1,2,5]OXADIAZOLO[3,4-B]PYRIDINE-CARBOXYLATE

This invention relates to a novel process for making alkyl 7-amino-5-methyl-[1,2,5]-oxadiazolo[3,4-b]pyridine-carboxylate.

Benzimidazole bifurazan series compounds and synthesis method thereof

The invention provides benzimidazole bifurazan series compounds and a synthesis method thereof. The molecular structure of the compounds is represented by a formula I, wherein R1 is selected from hydrogen, halogen, trifluoromethyl, nitryl, amino, sulfo, methyl, tert-butyl, methoxyl, carboxyl, ethoxyformyl or benzoyl; R2 is selected from hydrogen or fluorine. On the basis, the invention discloses an efficient method for preparing the series of compounds. The preparation method comprises the steps: synthesizing an intermediate 4-amino-1,2,5-oxadiazole-3-methoxyamidine by taking malononitrile asa starting raw material, carrying out a reaction on the intermediate with o-phenylenediamine or a substitute thereof under a heating reflux condition by taking acetic acid as a solvent, cooling, adding water, stirring to separate out a solid after the reaction is finished, and carrying out suction filtration, washing, drying and the like to obtain a final product. According to the method, a pure product can be obtained without recrystallization, column chromatography separation and other steps, the method is simple, rapid and practical, and the yield can generally reach 80% or above.