156469-74-8

Basic information

• Product Name: DIETHYL CIS-1-BENZYL-3,4-PYRROLIDINEDICARBOXYLATE
• Synonyms: DIETHYL CIS-1-BENZYL-3,4-PYRROLIDINEDICARBOXYLATE;D30210;cis-Diethyl 1-benzyl-3,4-pyrrolidinedicarboxylate;cis-Diethyl 1-benzylpyrrolidine-3,4-dicarboxylate;DIETHYL CIS-1-BENZYL-3,4-PYRROLIDINEDICARBOXYLAT;cis-1-(Phenylmethyl)-3,4-pyrrolidinedicarboxylic acid diethyl ester;IETHYL CIS-1-BENZYL-3,4-PYRROLIDINEDICARBOXYLATE
• CAS NO: 156469-74-8
• Molecular Formula: C17H23NO4
• Molecular Weight: 305.37
• Product Categories: pharmacetical
• Mol File: 156469-74-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 394.6°Cat760mmHg
• Flash Point: 192.4°C
• Appearance: /
• Density: 1.146g/cm³
• Storage Temp.: 2-8°C
• PKA: 7.13±0.60(Predicted)
• CAS DataBase Reference: DIETHYL CIS-1-BENZYL-3,4-PYRROLIDINEDICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL CIS-1-BENZYL-3,4-PYRROLIDINEDICARBOXYLATE(156469-74-8)
• EPA Substance Registry System: DIETHYL CIS-1-BENZYL-3,4-PYRROLIDINEDICARBOXYLATE(156469-74-8)

Safety Data

• Hazardous Substances Data: 156469-74-8(Hazardous Substances Data)

Usage

General Description

DIETHYL CIS-1-BENZYL-3,4-PYRROLIDINEDICARBOXYLATE is a chemical compound that falls under the category of pyrrolidine dicarboxylates. It is typically used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. DIETHYL CIS-1-BENZYL-3,4-PYRROLIDINEDICARBOXYLATE has the potential to act as a central nervous system depressant due to its structural similarity to other sedative-hypnotic drugs. It is important to handle this chemical with care and follow proper safety protocols when working with it in a laboratory setting.

Upstream product

• 93102-05-7 N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine 
• 623-91-6 diethyl Fumarate 
• 50-00-0 formaldehyd 
• 17136-36-6 N-benzylglycine 
• 141-05-9 Diethyl maleate 
• 53215-95-5 N-(trimethylsilylmethyl)benzylamine 
• 79909-16-3 1,4-Bis(ethoxy)-1,4-bis(trimethylsiloxy)-1,3-butadien 
• 92486-61-8 Benzyl-bis-methylsulfanylmethyl-amine 

Downstream Products

• 1345831-65-3 (trans-1-benzylpyrrolidine-3,4-diyl)dimethanol 
• 865451-74-7 (3R,4R)-4-[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)phenylcarbamoyl]pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester 
• 911114-86-8 (3S,4R)-3-[(cyclohexylmethyl-methyl-carbamoyloxy)-methyl]-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 911113-73-0 (3R,4R)-3-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-4-[(2-methyl-2-phenyl-propionylamino)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 895245-26-8 (3S,4R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 911113-74-1 (3R,4S)-3-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-4-methanesulfonyloxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 911113-76-3 (3S,4R)-3-azidomethyl-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 911113-78-5 (3R,4R)-3-aminomethyl-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 895245-25-7 (3S,4R)-3-hydroxymethyl-4-({isopropyl-[4-methoxy-3-(3-methoxy-propoxy)-benzoyl]-amino}-methyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 1393732-25-6 tert-butyl trans-3,4-bis(hydroxymethyl)pyrrolidin-1-carboxylate 
• 895245-30-4 (3S,4S)-3,4-bis-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 895245-32-6 (3R,4R)-tert-butyl 3,4-bis(hydroxymethyl)pyrrolidine-1-carboxylate 
• 1212409-03-4 ((3SR,4SR)-1-tert-butoxycarbonyl)4-(ethoxycarbonyl)pyrrolidine-3-carboxylic acid 
• 595556-31-3 (R,R)-pyrrolidine-1,3,4-tricarboxylic acid 1-tert-butyl ester 3-ethyl ester 

Relevant articles and documents

[3+2] Dipolar cycloadditions of an unstabilised azomethine ylide under continuous flow conditions

The [3+2] dipolar cycloaddition reactions of the unstabilised azomethine ylide precursor benzyl(methoxymethyl)(trimethylsilylmethyl)amine with 12 electron-deficient alkenes in the presence of catalytic trifluoroacetic acid are examined under continuous fl

PROCESSES FOR THE PREPARATION OF (3R, 4R) -N- (4 -CHLOROPHENYL) -1- (2, 2-DIFLUOROETHYL) -N' - [2-FLUORO-4- (2-OXO-1 (2H) -PYRIDINYL) PHENYL] -3, 4-PYRROLIDINEDICARBOXAMIDE

The invention is concerned with processes for the manufacture of pyrrolidine-3,4- dicarboxamide derivative of formula (I), and the intermediates useful for those processes.

Tris(pentafluorophenyl)borane-catalyzed synthesis of N-benzyl pyrrolidines

1,3-Dipolar cycloaddition of in situ generated azomethine ylides to electron deficient olefins catalyzed tris(pentafluorophenyl)borane is described. Georg Thieme Verlag Stuttgart.