156730-49-3 Usage
Explanation
Different sources of media describe the Explanation of 156730-49-3 differently. You can refer to the following data:
1. The compound consists of 26 carbon atoms, 29 hydrogen atoms, and 3 nitrogen atoms.
2. The complex structure includes two benzene rings (six-membered carbon rings) with a phenylethyl group (a phenyl group attached to an ethyl chain) on each ring, linked by a central ethane (two-carbon) backbone.
3. The compound has two non-superimposable mirror image forms, which means it can exist as two different isomers with the same molecular formula but different spatial arrangements.
4. As a chiral molecule, 1S,2S-bis[(1R)-1-phenylethyl]-1,2-diphenyl-1,2-ethanediamine can be used as a chiral ligand in asymmetric synthesis reactions, helping to create chiral products with high selectivity.
5. The compound is often used in metal-catalyzed asymmetric hydrogenation processes, which involve the addition of hydrogen to a molecule in a chiral-selective manner, resulting in the formation of chiral products.
6. Researchers have studied 1S,2S-bis[(1R)-1-phenylethyl]-1,2-diphenyl-1,2-ethanediamine for its potential use in organic electronic materials, such as in the development of organic solar cells or organic light-emitting diodes (OLEDs).
7. The compound can be used as a chiral selector in chromatography, a technique for separating and analyzing mixtures of compounds. As a chiral selector, it can help to separate and analyze chiral compounds based on their different interactions with the chiral selector.
Molecular structure
Two benzene rings with phenylethyl groups attached, connected by an ethane backbone
Chiral molecule
存在两种非超posable的镜像异构体
Chiral ligand
Used in asymmetric synthesis reactions
Metal-catalyzed asymmetric hydrogenation
Involved in hydrogenation processes
Organic electronic materials
Potential applications in the field
Chiral selector in chromatography
Used for separating chiral compounds
Check Digit Verification of cas no
The CAS Registry Mumber 156730-49-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,7,3 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 156730-49:
(8*1)+(7*5)+(6*6)+(5*7)+(4*3)+(3*0)+(2*4)+(1*9)=143
143 % 10 = 3
So 156730-49-3 is a valid CAS Registry Number.
156730-49-3Relevant articles and documents
Simple Synthesis of a C2 Symmetric Vicinal Diamine: Highly Diastereoselective Grignard Addition toa Chiral Bis-Imine
Bambridge, Kimberley,Begley, Michael J.,Simpkins, Nigel S.
, p. 3391 - 3394 (1994)
The reaction of the enantiomerically pure bis-imine derived from glyoxal and (R)-α-methylbenzylamine with PhMgCl in diethylether is highly diastereoselective , resulting in the selective formation of the C2 symmetric vicinal diamine 7.
Design, development, and scale-up of a selective meso-epoxide desymmetrization process
Varie, David L.,Beck, Christopher,Borders, Sandra K.,Brady, Molly D.,Cronin, Jason S.,Ditsworth, Tracy K.,Hay, David A.,Hoard, David W.,Hoying, Richard C.,Linder, Ryan J.,Miller, Richard D.,Moher, Eric D.,Remacle, Jacob R.,Rieck III, John A.,Anderson, David D.,Dodson, Paul N.,Forst, Mindy B.,Pierson, Duane A.,Turpin, Joseph A.
, p. 546 - 559 (2012/12/31)
A pilot-plant scale desymmetrization of the cyclic meso-epoxide 4b, using a chiral lithium amide prepared from symmetrical diamine 17, was designed and implemented to provide allylic alcohol 3b in high yield and greater than 99% ee. This chiral alcohol was converted to ketone 2b, a key intermediate in a new asymmetric synthesis of LY459477. Chiral diamine 17 was prepared from a readily available chiral precursor, (R)-α-methylbenzylamine, and could be recovered from the reaction mixture and reused. Studies performed to probe the mechanism of the rearrangement reaction of epoxide 4b showed that diamine 17 provided an optimal combination of selectivity and scaleability for this process.
