156743-05-4Relevant articles and documents
Practical synthesis of the putative polyamine spider toxin FTX: A proposed blocker of voltage-sensitive calcium channels
Blagbrough, Ian S.,Moya, Eduardo
, p. 2057 - 2060 (1994)
FTX (FTX-3.3), a putative polyamine toxin from American funnel-web spiders, has been synthesized from tri-CBZ-L-arginine. Raney nickel mediated desulfurization of a thioamide, generated selectively with Lawesson's reagent in the presence of the benzyloxyc
Efficient syntheses of polyamine and polyamine amide voltage-sensitive calcium channel blockers: FTX-3.3 and sFTX-3.3
Moya, Eduardo,Blagbrough, Ian S.
, p. 179 - 182 (2007/10/03)
Efficient syntheses of FTX-3.3 and sFTX-3.3, voltage-sensitive calcium channel blockers are described. These modified polyamines were prepared from selectively protected polyamines and purified on a practical scale.