157282-77-4

Upstream product

• 49629-37-0 2-(4-methoxybenzylidene)-1-tetralone 
• 123-11-5 4-methoxy-benzaldehyde 
• 17356-08-0 thiourea 
• 79-04-9 chloroacetyl chloride 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 134408-32-5 9-(4-chlorophenyl)-7-(4-methoxyphenyl)-6,7-dihydro-5H-benzo[h]thiazolo[2,3-b]quinazoline 
• 3028-02-2 N-benzothiazol-2-yl-2-chloroacetamide 
• 587-65-5 N-chloroacetyl-aniline 
• 79-11-8 chloroacetic acid 

Downstream Products

• 1222377-07-2 (Z)-3-(5-((7-(4-methoxyphenyl)-9-oxo-5H-benzo[h]thiazolo[2,3-b]quinazolin-10(6H,7H,9H)-ylidene)methyl)furan-2-yl)-4-methylbenzoic acid 
• 1222376-82-0 (Z)-3-((2-methoxy-4-((7-(4-methoxyphenyl)-9-oxo-5H-benzo[h]thiazolo[2,3-b]quinazolin-10(6H,7H,9H)-ylidene)methyl)phenoxy)methyl)benzoic acid 

Relevant academic research and scientific papers

Recyclable task-specific acidic ionic liquid [NMP]H2PO4: Microwave-assisted, efficient one-pot, two-step tandem synthesis of fused thiazolo[2,3-b]quinazolinone and thiazolo[2,3-b]quinazoline derivatives

A novel, time-effective, eco-conscious and microwave-assisted tandem one-pot, two-step reaction has been described for the synthesis of thiazolo[2,3-b]quinazolinone (4a-f) and thiazolo[2,3-b]quinazoline (5a-t) derivatives in quantitative yield in the pres

Synthesis of fused thiazolo[3,2-a]pyrimidinones: N-aryl-2-chloroacetamides as doubly electrophilic building blocks

2-Chloro-N-phenylacetamide and N-(benzo[d]thiazol-2-yl)-2-chloroacetamide are doubly electrophilic building blocks for the formation of ring annulated thiazolo[3,2-a]pyrimidinone products. This synthetic route involves formation of the title compound in acceptable product yields by the elimination of the by-product, aniline/2-aminobenzothiazole. Analytical and spectral studies, as well as single crystal X-ray data on the representative compound 6c confirmed the structure of all the reaction products.

Heterocyclic systems containing bridgehead nitrogen atom: Part LXXV - Syntheses of thiazolobenzoquinazolines and thiazinobenzoquinazolines

2-Arylidenetetralin-1-ones (1a-c) on condensation with thiourea give 4-aryl-3,4,5,6-tetrahydrobenzoquinazoline-2(1H)-thiones (2a-c) which on reaction with chloroacetic acids, α- and β-halopropionic acids afford 5-aryl-2,3,6,7-tetrahydro-3-oxo-5H-thiazo