157381-11-8

Basic information

• Product Name: C₂₄H₃₄ClNO₁₈
• CAS NO: 157381-11-8
• Molecular Weight: 659.983
• Mol File: 157381-11-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 976.0±65.0 °C(Predicted)
• Density: 1.79±0.1 g/cm3(Predicted)
• CAS DataBase Reference: C₂₄H₃₄ClNO₁₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₃₄ClNO₁₈(157381-11-8)
• EPA Substance Registry System: C₂₄H₃₄ClNO₁₈(157381-11-8)

Safety Data

• Hazardous Substances Data: 157381-11-8(Hazardous Substances Data)

Upstream product

• 1512800-77-9 C₄₈H₇₄ClNO₃₈ 
• 198561-63-6 2-chloro-4-nitrophenyl O-(α-D-glucopyranosyl)-(1->4)-tetrakis-[O-α-D-glucopyranosyl-(1->4)]-β-D-glucopyranoside 
• 90826-64-5 2-chloro-4-nitrophenyl β-maltoheptoside 
• 145072-72-6 o-chloro-p-nitrophenyl β-maltotetraoside 
• 99304-80-0 2-chloro-4-nitrophenyl-β-maltopentoside 
• 61139-07-9 1,2,3,6-tetra-O-acetyl-4-O-(2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-α-D-glucopyranosyl)-D-glucopyranose 
• 619-08-9 2-chloro-4-nitrophenol 
• 76821-27-7 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl-(1->4)-2,3,6-tri-O-acetyl-α-D-glucopyranosyl-(1->4)-2,3,6-tri-O-acetyl-α-D-glucopyranosyl-bromide 

Downstream Products

• 492-61-5 β-D-glucose 
• 619-08-9 2-chloro-4-nitrophenol 
• 1554036-64-4 4,6-O-benzylidene-2-chloro-4-nitrophenyl cellotrioside 
• 6401-81-6 maltotriose 

Relevant articles and documents

A chromogenic assay for limit dextrinase and pullulanase activity

A new chromogenic substrate to assay the starch debranching enzymes limit dextrinase and pullulanase is described. The 2-chloro-4-nitrophenyl glycoside of a commercially available branched heptasaccharide (Glc-maltotriosyl- maltotriose) was found to be a suitable specific substrate for starch debranching enzymes and allows convenient assays of enzymatic activities in a format suited for high-throughput analysis. The kinetic parameters of these enzymes toward the synthesized substrate are determined, and the selectivity of the substrate in a complex cereal-based extract is established.

Chemoenzymatic preparation of 2-chloro-4-nitrophenyl β-maltooligosaccharide glycosides using glycogen phosphorylase b

In the present work, we aimed to develop a new chemoenzymatic procedure for the synthesis of β-maltooligosaccharide glycosides. The primer in the enzymatic reaction was 2-chloro-4-nitrophenyl β-maltoheptaoside (G7-CNP), which was synthesised from β-cyclodextrin (β-CD) using a very convenient chemical method [E. Farkas, L. Janossy, J. Harangi, L. Kandra, A. Liptak, Carbohydr. Res., 303 (1997) 407-415]. Shorter chain length CNP-maltooligosaccharides in the range of dp 3-6 were prepared using rabbit skeletal muscle glycogen phosphorylase b (EC 2.4.1.1). Detailed enzymological investigations revealed that the conversion of G7-CNP was highly dependent on the conditions of phosphorolysis. A 100% conversion of G7-CNP was achieved during 10 min in 1 M phosphate buffer (pH 6.8) at 30°C with the tetramer glycoside (77%) as the main product. Phosphorolysis at 10°C for 10 min resulted in 89% conversion and G4-, G5-, and G6-CNP oligomers were detected in the ratio of 29:26:34%, respectively. The reaction pattern was investigated using an HPLC system. The preparative scale isolation of G(3→6)-CNP glycosides was achieved by size-exclusion column chromatography (SEC) on Toyopearl HW-40 matrix. The productivity of the synthesis was improved by yields of up to 70-75%. Copyright (C) 1999 Elsevier Science Ltd.