15745-68-3

Basic information

• Product Name: (E)-1-phenyl-3-phenylsulfanyl-2-propen-1-one
• Synonyms: (E)-1-phenyl-3-phenylsulfanyl-2-propen-1-one
• CAS NO: 15745-68-3
• Molecular Weight: 240.326
• Mol File: 15745-68-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-1-phenyl-3-phenylsulfanyl-2-propen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-phenyl-3-phenylsulfanyl-2-propen-1-one(15745-68-3)
• EPA Substance Registry System: (E)-1-phenyl-3-phenylsulfanyl-2-propen-1-one(15745-68-3)

Safety Data

• Hazardous Substances Data: 15745-68-3(Hazardous Substances Data)

Upstream product

• 78080-37-2 (E)-1-Phenyl-3-phenylsulfanyl-but-2-en-1-one 
• 78080-40-7 (E)-4-phenylthiopent-3-en-2-one 
• 53963-28-3 (E)-1-phenyl-3,3-bis(phenylthio)propene 
• 108-98-5 thiophenol 
• 3623-15-2 phenyl propargyl ketone 

Downstream Products

• 882-33-7 diphenyldisulfane 
• 78080-37-2 (E)-1-Phenyl-3-phenylsulfanyl-but-2-en-1-one 
• 78080-40-7 (E)-4-phenylthiopent-3-en-2-one 
• 70769-84-5 3-hydroxy-1-phenylbutyl phenyl sulphide 
• 70769-78-7 (Z)-4-Phenyl-4-phenylsulfanyl-but-3-en-2-one 
• 70769-75-4 (Z)-1-Phenyl-3-phenylsulfanyl-but-2-en-1-one 
• 70769-79-8 (Z)-4-phenylthiopent-3-en-2-one 
• 15724-82-0 (Z)-1-phenyl-3-phenylsulfanyl-2-propen-1-one 
• 70769-82-3 1-Phenyl-3-phenylsulfanylpropanol 
• 108-98-5 thiophenol 
• 104-55-2 3-phenyl-propenal 
• 960-40-7 cis-1-Benzoyl-2-phenylsulfonyl-ethylen 
• 10470-04-9 trans-1,4-diphenylcyclohexane 

Relevant articles and documents

Sulfonium Ylides by (3+2) Cycloaddition of Arynes with Vinyl Sulfides: Stereoselective Synthesis of Highly Substituted Alkenes

The reaction of in situ generated arynes with vinyl sulfides provides benzannulated sulfonium ylides in a (3+2) cycloaddition. Trapping of the intermediate ylides with electrophiles (proton transfer or a second aryne addition) and subsequent β-elimination give rise to di-, tri-, or tetrasubstituted alkenes with high stereoselectivity. Experimental studies and DFT calculations provide insight into the mechanisms of these cascade reactions.

Reduction of β-Arylthio- or β-Alkylthio-αβ-Unsaturated Ketones

The preparation and reduction of β-arylthio or β-alkylthio-αβ-unsaturated ketones (1) with lithium aluminium hydride or sodium borohydride have been examined.Reduction of the ketones (1) with lithium aluminium hydride gave αβ-unsaturated ketones (2), in which the olefinic (R1) and carbonyl (R2) substituents are reversed compared with the starting αβ-unsaturated ketone (1), or the saturated γ-hydroxy-sulphides (3).Reduction of the ketones (1) with sodium borohydride afforded only the αβ-unsaturated ketones (2).Reduction of (1) with sodium borohydride in the presence of metal halides gave the saturated ketones (5).