70769-75-4

Upstream product

• 85143-88-0 1-(3-phenyl-3-oxo-1-buten-1-yl)-3-methylimidazolium iodide 
• 108-98-5 thiophenol 
• 93-91-4 1-phenylbutan-1,3-dione 
• 91859-93-7 3-(1-benzimidazolyl)-1-phenyl-2-buten-1-one 
• 91164-76-0 3-(1-triazolyl)-1-phenyl-2-buten-1-one 
• 63525-16-6 1-phenyl-3-chloro-2-buten-1-one 
• 83996-14-9 1-phenyl-3-(1-imidazolyl)-2-buten-1-one 
• 78080-40-7 (E)-4-phenylthiopent-3-en-2-one 
• 15745-68-3 (E)-1-phenyl-3-phenylsulfanyl-2-propen-1-one 
• 86573-89-9 3-Benzenesulfinyl-1-phenyl-3-trimethylsilanyl-cyclobutanol 
• 91859-96-0 3-(3,5-dimethyl-1-pyrazolyl)-1-phenyl-2-buten-1-one 
• 76973-17-6 1-phenyl-3-(1-imidazolyl)-2-buten-1-one 
• 91164-85-1 1-Methyl-3-((Z)-1-methyl-3-oxo-3-phenyl-propenyl)-3H-benzoimidazol-1-ium; iodide 
• 91164-86-2 4-Methyl-1-((Z)-1-methyl-3-oxo-3-phenyl-propenyl)-1H-[1,2,4]triazol-4-ium; iodide 

Downstream Products

• 42392-88-1 1-phenyl-3-methoxybut-2-en-1-one 
• 5050-65-7 3-phenyl-5-methyl-Δ²-isoxazoline 
• 7064-06-4 3-methyl-5-phenyl-4,5-dihydroisoxazole 
• 77252-93-8 (E)-3-Isopropoxy-1-phenyl-but-2-en-1-one 
• 108-98-5 thiophenol 

Relevant academic research and scientific papers

The Compounds Related to 3-(1-Imidazolyl)-2-alken-1-ones. Preparation and Reactions

Compounds related to 3-(1-imidazolyl)-2-alken-1-ones, 3-(1-imidazolyl)-2-alkenoic acid derivatives and 2-alken-1-ones having heterocycles on the C-3 carbon were prepared.The reaction of nucleophiles with these compounds was also discussed.

THE SILA-PUMMERER REARRANGEMENT OF 1-ALKYL-3-PHENYLSULFINYL-3-TRIMETHYLSILYLCYCLOBUTANOLS. A NEW METHOD FOR THE PREPARATION OF 3-ALKYL-2-CYCLOBUTENONES

3-Alkyl-2-cyclobutenones were produced by the sila-Pummerer rearrangement of 1-acetoxy-1-alkyl-3-phenylsulfinyl-3-trimethylsilylcyclobutanes followed by hydrolysis. β-Phenylthio-α,β- and β,γ-unsaturated ketones were major products when the corresponding cyclobutanols were employed.

The Reaction of 3-(1-Imidazolyl)-2-alken-1-ones with Nucleophiles

Generally 3-hetero-substituted 2-alken-1-ones were prepared from 1,3-alkanediones, 3-chloro-2-alken-1-ones, or conjugated ynones.The preparation of 3-hetero-substituted 2-alken-1-ones was subjected to some limitations by these methods.By the reaction of 3-(1-imidazolyl)-2-alken-1-ones (I) and 3-(3-oxo-1-alkenyl)-1-methylimidazolium iodides (II) with nucleophiles, 3-hetero-substituted 2-alken-1-ones could be obtained regioselectively in good yield under mild conditions.These results suggested that compounds I and II were concluded to be useful intermediates for the organic synthesis.

Reduction of β-Arylthio- or β-Alkylthio-αβ-Unsaturated Ketones

The preparation and reduction of β-arylthio or β-alkylthio-αβ-unsaturated ketones (1) with lithium aluminium hydride or sodium borohydride have been examined.Reduction of the ketones (1) with lithium aluminium hydride gave αβ-unsaturated ketones (2), in which the olefinic (R1) and carbonyl (R2) substituents are reversed compared with the starting αβ-unsaturated ketone (1), or the saturated γ-hydroxy-sulphides (3).Reduction of the ketones (1) with sodium borohydride afforded only the αβ-unsaturated ketones (2).Reduction of (1) with sodium borohydride in the presence of metal halides gave the saturated ketones (5).