157563-52-5Relevant articles and documents
Enantioselective Synthesis of 4-Allyl Tetrahydroquinolines via Copper(I) Hydride-Catalyzed Hydroallylation of 1,2-Dihydroquinolines
Xu-Xu, Qing-Feng,You, Shu-Li,Zhang, Xiao
, p. 1530 - 1534 (2020)
CuCl/(R,R)-Ph-BPE-catalyzed asymmetric hydroallylation of 1,2-dihydroquinolines, prepared from readily available quinolines, was developed. The optically active tetrahydroquinolines (THQs) bearing an allylic functionality at position 4 were obtained in good yields and excellent enantioselectivity. The introduced allylic groups are amenable to diverse transformations, thus offering chances to rapidly expand the THQ libraries.
Enantioselective bromocyclization of allylic amides catalyzed by BINAP derivatives
Kawato, Yuji,Kubota, Akino,Ono, Hiromi,Egami, Hiromichi,Hamashima, Yoshitaka
supporting information, p. 1244 - 1247 (2015/03/14)
A highly enantioselective bromocyclization of allylic amides with N-bromosuccinimide (NBS) was developed with DTBM-BINAP as a catalyst, affording chiral oxazolines with a tetrasubstituted carbon center in high yield with up to 99% ee. By utilizing the bro
Nickel-catalyzed enantioselective hydrovinylation of silyl-protected allylic alcohols: An efficient access to homoallylic alcohols with a chiral quaternary center
Zhang, Qi,Zhu, Shou-Fei,Cai, Yan,Wang, Li-Xin,Zhou, Qi-Lin
experimental part, p. 1899 - 1906 (2011/02/25)
Asymmetric hydrovinylation of silyl-protected allylic alcohols catalyzed by nickel complexes of chiral spiro phosphoramidite ligands was developed. A series of homoallylic alcohols with a chiral quaternary center were produced in high yields (up to 97%) and high enantioselectivities (up to 95% ee). The reaction provides an efficient method for preparing bifunctional compounds with a chiral quaternary carbon center.
