157733-10-3Relevant academic research and scientific papers
Convergent synthesis of a key intermediate for hypocholesterolemic agent 1233A, starting from methyl 3-hydroxy-2-methylpropanoate and asymmetrized bis(hydroxymethyl)acetaldehyde (BHYMA*)
Guanti, Giuseppe,Banfi, Luca,Schmid, Giovanna
, p. 4239 - 4242 (2007/10/02)
Compound 2, which is a known intermediate for the total synthesis of hypocholesterolemic agent 1233A 1, has been synthesized in good overall yield through a convergent approach, employing 3-hydroxy-2-methylpropanoate 6 and BHYMA* 5 as chiral building bloc
