94807-93-9Relevant academic research and scientific papers
Stereoselective synthesis of the macrolactone core of (+)-neopeltolide
Raghavan, Sadagopan,Samanta, Pradip Kumar
, p. 2346 - 2349 (2012/07/01)
A stereoselective synthesis of the macrolactone core of the potent anticancer agent neopeltolide is disclosed. The key steps of the synthesis include asymmetric allylation using Krische' protocol, conjugate reduction using MacMillan's methodology, and an
Convergent synthesis of a key intermediate for hypocholesterolemic agent 1233A, starting from methyl 3-hydroxy-2-methylpropanoate and asymmetrized bis(hydroxymethyl)acetaldehyde (BHYMA*)
Guanti, Giuseppe,Banfi, Luca,Schmid, Giovanna
, p. 4239 - 4242 (2007/10/02)
Compound 2, which is a known intermediate for the total synthesis of hypocholesterolemic agent 1233A 1, has been synthesized in good overall yield through a convergent approach, employing 3-hydroxy-2-methylpropanoate 6 and BHYMA* 5 as chiral building bloc
Baker's Yeast Reduction of 3-Phenylthiomethyl-2-butenolide and Its Derivatives: Synthesis of Versatile Chiral C5-Building Blocks for Terpenoid Synthesis
Takabe, Kunihiko,Hiyoshi, Hidetaka,Sawada, Hiroyuki,Tanaka, Masaya,Miyazaki, Akira,et al.
, p. 1399 - 1400 (2007/10/02)
Bakers' yeast reduction of 3-phenylthiomethyl-2-butenolide gave (R)-3-phenylthiomethylbutanolide (99percent e.e.), a versatile chiral C5-building block for terpenoid synthesis.
PREPARATION OF CHIRAL C5-BUILDING BLOCKS FOR TERPENE SYNTHESIS BY BAKERS' YEAST REDUCTION OF SULFUR-FUNCTIONALIZED PRENYL DERIVATIVES
Sato, Toshio,Hanayama, Kyoko,Fujisawa, Tamotsu
, p. 2197 - 2200 (2007/10/02)
Enantioselective hydrogenation of several α,β-unsaturated aldehydes and allylic alcohols of sulfur-functionalized prenyl derivatives with bakers' yeast gave bifunctional chiral (S)- and (R)-C5-building blocks for terpene synthesis with high enantiomeric e
