157758-30-0

Basic information

• Product Name: (S)-3-((tert-butyldimethylsilyl)oxy)-4-((tert-butyldiphenylsilyl)oxy)butanal
• Synonyms: (S)-3-((tert-butyldimethylsilyl)oxy)-4-((tert-butyldiphenylsilyl)oxy)butanal
• CAS NO: 157758-30-0
• Molecular Weight: 456.773
• Mol File: 157758-30-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-((tert-butyldimethylsilyl)oxy)-4-((tert-butyldiphenylsilyl)oxy)butanal(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-((tert-butyldimethylsilyl)oxy)-4-((tert-butyldiphenylsilyl)oxy)butanal(157758-30-0)
• EPA Substance Registry System: (S)-3-((tert-butyldimethylsilyl)oxy)-4-((tert-butyldiphenylsilyl)oxy)butanal(157758-30-0)

Safety Data

• Hazardous Substances Data: 157758-30-0(Hazardous Substances Data)

Upstream product

• 124655-05-6 (S)-methyl 4-(tert-butyldiphenylsilyloxy)-3-hydroxybutanoate 

Downstream Products

• 1093663-02-5 (7R,9S)-10-(tert-butyldiphenylsilyloxy)dec-5-yne-1,7,9-triol 
• 1093662-96-4 (7R,9S)-10-((tert-butyldiphenylsilyl)oxy)dec-5-yne-1,7,9-triol 
• 1093663-69-4 (6S,8S)-6-((tert-butyldimethylsilyl)oxy)-2,2,16,16,17,17-hexamethyl-3,3-diphenyl-4,15-dioxa-3,16-disilaoctadec-9-yn-8-ol 
• 1093663-71-8 (6S,8R)-6-((tert-butyldimethylsilyl)oxy)-2,2,16,16,17,17-hexamethyl-3,3-diphenyl-4,15-dioxa-3,16-disilaoctadec-9-yn-8-ol 
• 157758-38-8 1-[(2S,3S,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxy)-3-methoxy-2-methyl-hexyloxymethyl]-4-methoxy-benzene 
• 157758-31-1 C₃₁H₅₀O₃Si₂ 
• 157758-37-7 (3S,4S,6S)-6-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-3-methyl-hept-1-en-4-ol 

Relevant articles and documents

A Convergent Approach to Swinholide A. Stereoselective Construction of the C3-C17 Fragment of Swinholide A

A strategy for a total synthesis of the cytotoxic dimeric macrolide swinholide A (1, Scheme 1) is outlined and a stereoselective construction of the suitably functionalized C3-C17 fragment 4, starting with building blocks 6, 7, 9 and 10 is described.