15784-35-7

Basic information

• Product Name: (4-NITRO-1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID
• Synonyms: (S)-2-((S)-3-Carboxymethyl-2-oxo-2,3-dihydro-imidazo[1,2-a]pyridin-3-yl)- succinic acid;2-(4-nitro-1,3-dioxoisoindolin-2-yl)acetic acid
• CAS NO: 15784-35-7
• Molecular Formula: C₁₀H₆N₂O₆
• Molecular Weight: 250.17
• Mol File: 15784-35-7.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 517.7 °C at 760 mmHg
• Flash Point: 266.9 °C
• Appearance: /
• Density: 1.706g/cm³
• Vapor Pressure: 1.53E-11mmHg at 25°C
• Refractive Index: 1.674
• CAS DataBase Reference: (4-NITRO-1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (4-NITRO-1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID(15784-35-7)
• EPA Substance Registry System: (4-NITRO-1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID(15784-35-7)

Safety Data

• Statements: 36
• Safety Statements: 26
• RIDADR: UN 2811 6.1 / PGIII
• Hazardous Substances Data: 15784-35-7(Hazardous Substances Data)

Usage

General Description

(4-NITRO-1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID is a chemical compound with the molecular formula C10H7NO6. It is a yellow solid that is often used in research and chemical synthesis. The compound contains a nitro group and a dioxo group, making it a potential oxidizing agent and a precursor to other compounds with similar functionalities. It may also have pharmaceutical applications due to its structural similarity to certain drug molecules. Additionally, the presence of an acetic acid group gives the compound potential for use as a building block in organic chemistry synthesis. Overall, (4-NITRO-1,3-DIOXO-1,3-DIHYDRO-ISOINDOL-2-YL)-ACETIC ACID has several potential applications in various fields of research and industry.

InChI:InChI=1/C10H6N2O6/c13-7(14)4-11-9(15)5-2-1-3-6(12(17)18)8(5)10(11)16/h1-3H,4H2,(H,13,14)

Upstream product

• 857802-00-7 N,N-(3-nitro-phthaloyl)-glycine-nitrile 
• 641-70-3 3-nitrophthalic acid anhydride 
• 603-11-2 3-nitrophthalic acid 
• 56-40-6 glycine 

Downstream Products

• 1431564-99-6 (S)-4-(2-(2-(4-amino-1,3-dioxoisoindolin-2-yl)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide 
• 10133-86-5 3-Amino-phthalimido-N-essigsaeure 
• 1446318-11-1 C₁₈H₁₇N₃O₇ 
• 1003729-23-4 C₁₈H₁₅N₃O₆ 
• 1431566-27-6 (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(4-(2-methoxyacetamido)-1,3-dioxoisoindolin-2-yl)acetoxy)ethyl)pyridine 1-oxide 
• 1431564-98-5 (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)-phenyl)-2-(2-(4-nitro-1,3-dioxoisoindolin-2-yl)acetoxy)ethyl)-pyridine 1-oxide 
• 311332-19-1 C₁₇H₁₃N₃O₅ 
• 88252-56-6 4-Nitro-2-(8-oxo-6-phenyl-5-thia-1-aza-bicyclo[4.2.0]oct-7-yl)-isoindole-1,3-dione 
• 88252-58-8 4-Nitro-2-(8-oxo-6-phenyl-5-oxa-1-aza-bicyclo[4.2.0]oct-7-yl)-isoindole-1,3-dione 

Relevant articles and documents

N-acetamido galactose modified 3-nitrophthalimide derivative, preparation method, application and liver targeting probe

The invention provides an N-acetamido galactose modified 3-nitrophthalimide derivative, a preparation method and an application of the N-acetamido galactose modified 3-nitrophthalimide derivative, anda liver targeting probe. The preparation method of the fluorescent probe is simple, and the obtained fluorescent probe takes N-acetamido galactose as a liver targeting group and 3-nitrophthalimide asa CO response group, can be used as a CO detection reagent, is good in selectivity and high in sensitivity, can target liver cells and liver tissues, and can be used for dynamically monitoring the COlevel.

SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION

Disclosed are small molecules against cereblon to enhance effector T cell function. Methodos of making thes molecules and methods of using them to treat various disease states are also disclosed.

Synthesis and screening of cyclooxygenase inhibitory activity of some 1,3-dioxoisoindoline derivatives

In this study, 15 compounds bearing N,Nphthaloylacetamide structure designed by the molecular simplification approach based on thalidomide structure were synthesized and evaluated for inhibitory potencies against cyclooxgenase (COX) isoenzymes, namely COX-1 and COX-2. The results suggested that the N,Nphthaloylacetamide structure, as a primary amide, has inhibitory activity against cyclooxygenase isoenzymes with a higher COX-1 selectivity. The conversion of the primary amide to secondary or tertiary derivatives lowered the potency but favored the COX-2 selectivity thus yielding the compounds with stronger COX-2 inhibiting activity. ECV · Editio Cantor Verlag.