15784-39-1

Basic information

• Product Name: 1,1'-Biphenyl, 4-(phenylethynyl)-
• Synonyms: 1-(4-biphenylyl)-2-phenylacetylene;4'-phenyl-1,2-diphenylacetylene;1,4-biphenyl-ethynylbenzene;4-(phenylethynyl)biphenyl;4-(phenylethynyl)-1,1'-biphenyl;1,1'-Biphenyl,4-(phenylethynyl)
• CAS NO: 15784-39-1
• Molecular Formula: C20H14
• Molecular Weight: 254.331
• Mol File: 15784-39-1.mol
• Article Data: 48

Chemical Properties

• CAS DataBase Reference: 1,1'-Biphenyl, 4-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-Biphenyl, 4-(phenylethynyl)-(15784-39-1)
• EPA Substance Registry System: 1,1'-Biphenyl, 4-(phenylethynyl)-(15784-39-1)

Safety Data

• Hazardous Substances Data: 15784-39-1(Hazardous Substances Data)

Upstream product

• 591-51-5 phenyllithium 
• 297154-60-0 1-([1,1'-biphenyl]-3-yl)-2-phenylethane-1,2-dione 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 1719-19-3 2-Methyl-4-phenyl-3-butyn-2-ol 
• 536-74-3 phenylacetylene 
• 589-87-7 1,4-bromoiodobenzene 
• 3958-47-2 triphenylindium 
• 250643-76-6 tris((2-phenyl)ethynyl)indium 
• 100-59-4 phenylmagnesium chloride 
• 13667-12-4 1-bromo-4-phenylethynylbenzene 
• 591-50-4 iodobenzene 
• 29079-00-3 4-ethynyl-1,1'-biphenyl 
• 5122-94-1 4-biphenylboronic acid 
• 637-44-5 phenylpropyolic acid 

Downstream Products

• 111288-94-9 2',5'-dimethyl-3',6'-diphenyl-p-quaterphenyl 
• 111288-88-1 8-biphenylyl-7,10-diethyl-9-phenylfluoranthene 
• 2039-69-2 (Z)-4-styryl-1,1'-biphenyl 
• 95950-88-2 2-([1,1′-biphenyl]-4-yl)-3-phenylquinoxaline 
• 1522379-03-8 2-([1,1'-biphenyl]-4-yl)-4-phenylquinazoline 
• 36803-53-9 1-([1,1′-biphenyl]-4-yl)-2-phenylethane-1,2-dione 
• 14310-35-1 4-phenethyl-1,1′-biphenyl 
• 21175-18-8 (E)-4-phenylstilbene 
• 23934-48-7 2',5',3',6'-tetraphenyl-p-quaterphenyl 
• 111288-92-7 8-biphenylyl-7,10-di-n-hexyl-9-phenylfluoranthene 

Relevant articles and documents

Immobilization of Pd catalysts on mesoporous silica for amine- and copper-free Sonogashira coupling reactions

Immobilization of catalysts on solid supports is a promising approach to combine the advantages of heterogeneous and homogeneous catalysts. Pd(PPh3)2Cl2, known as an extremely active homogeneous catalyst for the Sonogashira coupling reaction, has been immobilized on high-surface-area MCF (mesocellular foams)-type mesoporous silica powder modified with 3-aminopropyltriethoxysilane and subsequently with diphenylphosphine. The functionalized MCF-type silica and supported catalysts have been characterized by x-ray photoelectron spectroscopy (XPS), fourier transform infrared spectroscopy (FTIR), elemental analysis, nitrogen sorption porosimetry, and scanning electron microscopy (SEM). Such supported Pd catalysts have proven to be useful recyclable reagents for copper- and amine-free Sonogashira coupling reactions of haloaromatic compounds with terminal alkynes. Copyright Taylor & Francis Group, LLC.

Palladium-catalyzed decarbonylative sonogashira coupling of terminal alkynes with carboxylic acids

A direct decarbonylative Sonogashira coupling of terminal alkynes with carboxylic acids was achieved through palladium catalysis. This reaction did not use overstoichiometric oxidants, thus overcoming the homocoupling issue of terminal alkynes. Under the reaction conditions, a wide range of carboxylic acids including those bioactive ones could couple readily with various terminal alkynes, thus providing a relative general method for preparing internal alkynes.

Selective Phosphoranation of Unactivated Alkynes with Phosphonium Cation to Achieve Isoquinoline Synthesis

We herein develop a selective phosphoranation of alkynes with phosphonium cation, which directs a concise approach to isoquinolines from unactivated alkyne and nitrile feedstocks in a single step. Mechanistic studies suggest that the annulation reaction is initiated by the unprecedented phosphoranation of alkynes, thus representing a unique reaction pattern of phosphonium salts and distinguishing it from existing protocols that largely rely on the utilization of highly functionalized imines/oximes and/or highly polarized alkynes.