1580446-08-7Relevant academic research and scientific papers
Toward new classes of potent antibiotics: Synthesis and antimicrobial activity of novel metallosaldach-imidazolium salts
Elshaarawy, Reda F.M.,Janiak, Christoph
, p. 31 - 42 (2014)
Imidazolium salts (Im+-R2R3-Cl -) attached to the N,N′-bis(salicylidene)-(±)-trans-1,2- diaminocyclohexane (saldach) backbone (4a-f) have been designed and successfully applied for the synthesis of the corresponding mononuclear complexes with Mn(III) and Fe(III) ions. The molecular structures of the saldach ligands H 2(R1)2saldach(Im+-R 2R3-Cl-)2 (R1 = H, tert-Bu, R2 = H, Et, n-Bu, R3 = H, Me) and their [M(III)Cl{(R1)2saldach(Im+-R2R 3-Cl-)2}] (M = Mn, Fe) complexes have been established. The free ligands exist as the phenol-OH and not as the zwitterionic (imine)N-H+···-O(phenol) tautomer. Antimicrobial activity of the target compounds revealed higher potent antibacterial activity against Salmonella aureus, B. subtilis while less effective against E. coli and C. albicans and inactivity against A. flavus. Compound (4d) and its Fe(III) complex (6d) exhibit remarkable extra-potent bactericidal activity.
Catalytic asymmetric cycloaddition of CO2 to epoxides via chiral bifunctional ionic liquids
Duan, Shuhui,Jing, Xinyao,Li, Dandan,Jing, Huanwang
, p. 34 - 39 (2015/11/02)
A series of new chiral ionic liquid catalysts composed of the N,N'-bis(salicyclidene) cyclohexene diaminatocobalt and an imidazolium salt were designed, prepared and applied for the chiral cyclic carbonate synthesis from racemic epoxides and carbon dioxide. All reactions exhibit good enantioselectivity for the chiral cyclic carbonate without polycarbonate and other by-products. The order of The order of catalytic activity toward the axial anions is OAc- > CF3CO2- > CCl3CO2- > OTs- and the order of enantioselectivity is OTs- > OAc- > CCl3CO2- > CF3CO2-.
