158110-04-4Relevant articles and documents
Stereoselective total synthesis of cananginones (D-I) using Ireland-Claisen rearrangement as a key step
Kuilya, Tapan Kumar,Chatterjee, Shamba,Goswami, Rajib Kumar
, p. 2905 - 2918 (2014/04/17)
A strategy for stereoselective total synthesis of α-substituted γ-hydroxymethyl γ-butyrolactone containing bioactive natural products cananginones (D-I) has been developed using cheap and commercially available d-mannitol as a chiral pool. The Ireland-Cla
Enantioselective synthesis of the C1-C15 fragment of dolabelide C
Vincent, Aurélie,Prunet, Jo?lle
, p. 2269 - 2271 (2007/10/03)
A synthesis of the C1-C15 fragment of dolabelide C is reported. The key step is a diastereoselective Mukaiyama aldol reaction to form the C6-C7 bond, followed by reduction and deoxygenation of the carbonyl group at C5. The trisubstituted vinyl iodide is i
Total synthesis of (+)-rolliniastatin 1
Koert
, p. 2517 - 2520 (2007/10/02)
The first total synthesis of the naturally occurring acetogenin (+)-rolliniastatin 1 (1) has been achieved. A high degree of stereochemical control in the construction of the bis-THF system was accomplished by chelation controlled addition of functionalized organo-metallic reagents derived from 5 and 11 to α-alkoxy-aldehydes.