158267-01-7

Upstream product

• 75-44-5 phosgene 
• 92841-65-1 (4R,5S)-1,5-dimethyl-4-phenylimidazolidin-2-one 

Downstream Products

• 158267-02-8 (4S,5R)-3,4-dimethyl-5-phenylimidazolidin-2-one-1-carbohydroxamic acid 
• 158267-05-1 C₁₂H₁₃N₃O₃ 
• 158267-03-9 (1R,4S)-3-<(4S,5R)-3,4-dimethyl-5-phenylimidazolidin-2-one-1-carbonyl>-3-aza-2-oxabicyclo<2.2.2>oct-4-ene 
• 215257-46-8 (4S,5R)-1-(3,4-dimethyl-2-oxo-5-phenylimidazolidine)carboxamide 

Relevant academic research and scientific papers

Diastereoselective hetero-Diels-Alder cycloaddition of a C-nitroso compound prepared starting from a homochiral imidazolidin-2-one

By Swern oxidation of the hydroxamic acid 3, prepared from the homichiral imidazolidin-2-one 1, the transient C-nitroso derivative 4 is obtained, and its cycloaddition to either cyclohexadiene or cyclopentadiene proceeds with high diastereoselection, owin

Enantiopure derivatives of aza-baylis-hillman adducts by subsequent sn'-sn' reactions of acylcarbamates bearing a chiral auxiliary

Reactions of (4S,5R)-1-(3,4-Dimethyl-2-oxo-5-phenylimidazolidine) carbonylisocyanate (4) with appropriate Baylis-Hillman adducts 5 gave the corresponding acyl carbamates 6,7 as equimolar diastereomeric mixtures. These mixtures were treated with DABCO, to afford with moderate diastereoselection easily separable [2-(3",4"-dimethyl-2"-oxo-5"- phenylimidazolidine-1-carboxamido)(aryl)methyl]acrylates 8 and 9.