158469-55-7

Upstream product

• 78725-48-1 4-(2-methoxyphenoxy)benzaldehyde 
• 90-05-1 2-methoxy-phenol 
• 78338-67-7 4-(2'-methoxyphenoxy)benzonitrile 
• 623-00-7 4-bromobenzenecarbonitrile 
• 158469-49-9 4-(5-Iodo-2-methoxyphenoxy)benzonitrile 

Downstream Products

• 1342818-09-0 2',4-dimethoxy-4'-{2-[3-(4-formylphenoxy)-4-methoxyphenyl]ethyl}biphenyl-2-carbaldehyde 
• 1342818-10-3 2',4-dimethoxy-4'-{2-[3-(4-hydroxymethylphenoxy)-4-methoxyphenyl]ethyl}biphenyl-2-carbaldehyde 
• 1342818-12-5 Br^(1-)*C₄₉H₄₄O₅P⁽¹⁺⁾ 
• 1342818-13-6 2',4-dimethoxy-2-vinyl-4'-{2-[3-(4-vinylphenoxy)-4-methoxyphenyl]ethyl}biphenyl 
• 1342818-15-8 Br^(1-)*C₄₉H₄₃BrO₅P⁽¹⁺⁾ 
• 121404-89-5 1-<4-(2-hydroxymethyl-4-methoxyphenyl)-3-methoxyphenyl>-2-<3-(4-hydroxymethylphenoxy)-4-methoxyphenyl>ethane 
• 158469-53-5 3-<3-<4-(3-Hydroxy-1-(phenylsulfanyl)propyl)phenoxy>-4-methoxyphenyl>propionic acid 
• 158469-52-4 Ethyl (Z)-3-<3-<4-(3-hydroxy-1-(phenylsulfanyl)propyl)phenoxy>-4-methoxyphenyl>acrylate 
• 158469-54-6 4-Methoxy-14-(phenylsulfanyl)-2,11-dioxatricyclo<13.2.2.1^3,7>eicosa-1(18),3,5,7(20),1(19),16-hexaen-10-one 
• 158469-57-9 4-Hydroxy-14-(phenylsulfanyl)-2,11-dioxatricyclo<13.2.2.1^3,7>eicosa-1(18),3,5,7(20),1(19),16-hexaen-10-one 
• 1026324-32-2 Methyl 3-<4-(5-iodo-2-methoxyphenoxy)phenyl>-3-(phenylsulfanyl)propionate 

Relevant academic research and scientific papers

A Corey–Seebach Macrocyclisation Strategy for the Synthesis of Riccardin C and an Unnatural Macrocyclic Bis(bibenzyl) Analogue

A total synthesis of riccardin C has been accomplished using a Corey–Seebach reaction to effect macrocyclisation. The versatility of the strategy has also been demonstrated with a mimetic synthesis of an unnatural bis(bibenzyl) analogue.

Unified syntheses of cavicularin and riccardin C: Addressing the synthesis of an arene adopting a boat configuration

Concise syntheses of the natural products cavicularin (ten steps) and riccardin C (seven steps) are reported. Key features of the new synthetic route are a convergent strategy to assemble acyclic precursors and a sequence of regioselective reduction and h

Synthesis of (±)-combretastatin D-1 and combretastatin D-2

(±)-Combretastatin D-1 was synthesized in 16 steps by way of its congener, combretastatin D-2. In the key step, the strained 15-membered lactone ring was formed using high-dilution Mitsunobu conditions in 89% yield. Saturated seco acid 4 was a much better substrate for the cyclization reaction than the unsaturated seco acid 3.