1584705-57-6Relevant articles and documents
Preparation of Electrophilic Trifluromethylthio Reagents from Nucleophilic Tetramethylammonium Trifluoromethylthiolate
Kovács, Szabolcs,Bayarmagnai, Bilguun,Goossen, Lukas J.
, p. 250 - 254 (2017)
A straightforward synthetic entry to the principal classes of electrophilic trifluoromethylthiolating agents is presented. It draws on inexpensive, shelf-stable tetramethylammonium trifluoromethylthiolate (Me4N–SCF3) as the SCF3source in the place of stoichiometric coinage metal-SCF3complexes. (Figure presented.).
Rh(III)-Catalyzed Trifluoromethylthiolation of Indoles via C-H Activation
Wang, Qiang,Xie, Fang,Li, Xingwei
, p. 8361 - 8366 (2015)
Cp?Rh(III) complexes have been applied as efficient catalysts for the C-H activation and trifluoromethylthiolation of indoles functionalized with a heterocycle. With N-trifluoromethylthiosaccharin being an electrophilic SCF3 reagent, this C-S coupling occurred selectively at the 2-position with good functional group tolerance.
(Pentamethylcyclopentadienyl)cobalt(III)-Catalyzed Direct Trifluoromethylthiolation of Arenes via C?H Activation
Liu, Xu-Ge,Li, Qingjiang,Wang, Honggen
supporting information, p. 1942 - 1946 (2017/06/09)
The direct trifluoromethylthiolation of arenes was realized via (pentamethylcyclopentadienyl)cobalt(III)-catalyzed C(sp2)-H activation and coupling with AgSCF3 under the assistance of a directing group. The reaction features redox-neutrality, mild conditions, broad substrate scope, and good functional group tolerance. Preliminary mechanistic studies have been conducted. (Figure presented.).
